Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.71 |
| ▸ | RAB9A | P51151 | 6/20 | 0.71 |
| ▸ | MMP2 | P08253 | 3/20 | 0.65 |
| ▸ | MMP9 | P14780 | 3/20 | 0.65 |
| ▸ | MMP8 | P22894 | 3/20 | 0.65 |
| ▸ | MMP13 | P45452 | 3/20 | 0.65 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.60 |
| ▸ | GFER | P55789 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13599850 | 0.93 | NPC1 (0.81) | NPC1RAB9AMMP2MMP9MMP8 | |
| SCHEMBL14494924 | 0.93 | NPC1 (0.60) | NPC1RAB9AMMP2MMP9MMP8 | |
| SCHEMBL13183701 | 0.91 | NPC1 (0.78) | NPC1RAB9AMMP2MMP9MMP8 | |
| SCHEMBL7574964 | 0.91 | NPC1 (0.58) | NPC1RAB9AMMP2MMP9MMP8 | |
| SCHEMBL12172367 | 0.89 | NPC1 (0.72) | NPC1RAB9AMMP2MMP9MMP8 | |
| SCHEMBL20677813 | 0.86 | NPC1 (0.75) | NPC1RAB9AMMP2MMP9MMP8 | |
| SCHEMBL24347821 | 0.85 | NPC1 (0.53) | NPC1RAB9AMMP2MMP9MMP8 | |
| SCHEMBL6322764 | 0.85 | ALDH1A1 (0.76) | NPC1RAB9AMMP2MMP9MMP8 | |
| SCHEMBL22244598 | 0.85 | NPC1 (0.53) | NPC1RAB9AMMP2MMP9MMP8 | |
| SCHEMBL3337292 | 0.85 | GUSB (0.57) | NPC1RAB9AMMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9509008-B2 | Dibenzylated polybenzimidazole based polymer and method for preparing the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-11-29 | — | — | US | disclosed |
| US-20150311555-A1 | DIBENZYLATED POLYBENZIMIDAZOLE BASED POLYMER AND METHOD FOR PREPARING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-10-29 | — | — | US | disclosed |
| US-20120115050-A1 | METHOD FOR IN-SITU PREPARATION OF POLYBENZIMIDAZOLE-BASED ELECTROLYTE MEMBRANE AND POLYBENZIMIDAZOLE-BASED ELECTROLYTE MEMBRANE PREPARED THEREBY | KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2012-05-10 | — | — | US | disclosed |