Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.56 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14494924 | 0.98 | NPC1 (0.60) | NPC1RAB9ANPBWR1CHEK2SMN1; SMN2 | |
| SCHEMBL6124301 | 0.91 | NPC1 (0.71) | NPC1RAB9ANPBWR1CHEK2SMN1; SMN2 | |
| SCHEMBL13041697 | 0.91 | NPBWR1 (0.55) | NPC1RAB9ANPBWR1CHEK2SMN1; SMN2 | |
| SCHEMBL24347821 | 0.90 | NPC1 (0.53) | NPC1RAB9ANPBWR1CHEK2SMN1; SMN2 | |
| SCHEMBL31005275 | 0.90 | NPC1 (0.53) | NPC1RAB9ANPBWR1CHEK2SMN1; SMN2 | |
| SCHEMBL31005271 | 0.90 | NPC1 (0.53) | NPC1RAB9ANPBWR1CHEK2SMN1; SMN2 | |
| SCHEMBL2245390 | 0.90 | ALDH1A1 (0.61) | NPC1RAB9ANPBWR1SMN1; SMN2MEN1 | |
| SCHEMBL3337292 | 0.90 | GUSB (0.57) | NPC1RAB9ANPBWR1CHEK2SMN1; SMN2 | |
| SCHEMBL22244598 | 0.90 | NPC1 (0.53) | NPC1RAB9ANPBWR1CHEK2SMN1; SMN2 | |
| SCHEMBL7388566 | 0.90 | GUSB (0.57) | NPC1RAB9ANPBWR1CHEK2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230178854-A1 | WATER BASED POLYIMIDE-POWDER COATING COMPOSITION AND METHOD FOR MANUFACTURING COMPOSITE SEPARATOR FOR LITHIUM SECONDARY BATTERY USING SAME | XERABRID CO., LTD. (KR) | 2023-06-08 | — | — | US | disclosed |
| US-8247521-B2 | Acid-doped polyelectrolyte modified carbon nanotubes and their use in high temperature PEM fuel cell electrodes | ADVENT TECHNOLOGIES (GR) | 2012-08-21 | — | — | US | disclosed |
| US-8247521-B2 | Acid-doped polyelectrolyte modified carbon nanotubes and their use in high temperature PEM fuel cell electrodes | ADVENT TECHNOLOGIES (GR) | 2012-08-21 | — | — | US | disclosed |
| WO-2009087484-A2 | ACID-DOPED POLYELECTROLYTE MODIFIED CARBON NANOTUBES AND THEIR USE IN HIGH TEMPERATURE PEM FUEL CELL ELECTRODES | ADVENT TECHNOLOGIES (US) | 2009-07-16 | — | — | WO | disclosed |
| US-20090081487-A1 | Acid-Doped Polyelectrolyte Modified Carbon Nanotubes and their Use in High Temperature PEM Fuel Cell Electrodes | ADVENT TECHNOLOGIES (GR) | 2009-03-26 | — | — | US | disclosed |
| US-20090081487-A1 | Acid-Doped Polyelectrolyte Modified Carbon Nanotubes and their Use in High Temperature PEM Fuel Cell Electrodes | ADVENT TECHNOLOGIES (GR) | 2009-03-26 | — | — | US | disclosed |
| US-6476045-B2 | INDOLE AND AZAINDOLE DERIVATIVES AND THEIR USE AS TACHYKININ ANTAGONISTS, AND IN PARTICULAR AS NEUROKININ-1 RECEPTOR ANTAGONIST | MERCK SHARP & DOHME LTD. (GB) | 2002-11-05 | — | — | US | disclosed |
| US-20020022624-A1 | Azaindole derivatives and their use as therapeutic agents | MERCK SHARP & DOHME LTD. (GB) | 2002-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020022624-A1 | Azaindole derivatives and their use as therapeutic agents | HTR2B, HNMT, HTR1B | NPC1 3565/4885RAB9A 2962/4885NPBWR1 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.