SCHEMBL6124304

SCHEMBL6124304

Cc1ccc2[nH]c(-c3cccc(-c4nc5cc(C)ccc5[nH]4)c3)nc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.61
RAB9A P51151 9/20 0.61
SMN1; SMN2 Q16637 6/20 0.61
KDM4E B2RXH2 5/20 0.61
ALDH1A1 P00352 5/20 0.61
HPGD P15428 4/20 0.61
MAPT P10636 3/20 0.61
PKM P14618 3/20 0.61
TP53 P04637 2/20 0.61
GFER P55789 1/20 0.61
MMP2 P08253 1/20 0.55
MMP9 P14780 1/20 0.55
MMP8 P22894 1/20 0.55
MMP13 P45452 1/20 0.55
MEN1 O00255 2/20 0.53
POLB P06746 2/20 0.53
KMT2A Q03164 2/20 0.53
GAA P10253 2/20 0.53
USP2 O75604 1/20 0.53
BLM P54132 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21087331 0.95 NPC1 (0.60) NPC1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL12172367 0.94 NPC1 (0.72) NPC1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL3336231 0.90 NPC1 (0.62) NPC1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL14494924 0.87 NPC1 (0.60) NPC1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL20806658 0.87 NPC1 (0.52) NPC1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL7574964 0.86 NPC1 (0.58) NPC1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL1171203 0.85 NPC1 (0.51) NPC1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL14200106 0.85 NPC1 (0.48) NPC1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL7444528 0.84 KDM4E (0.71) NPC1RAB9ASMN1; SMN2KDM4EALDH1A1
SCHEMBL57009 0.84 POLB (0.57) NPC1RAB9ASMN1; SMN2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11718715-B2 Process for preparing polybenzimidazoles TECHNISCHE UNIVERSITÄT WIEN (AT) 2023-08-08 US disclosed
US-11718715-B2 Process for preparing polybenzimidazoles TECHNISCHE UNIVERSITÄT WIEN (AT) 2023-08-08 US disclosed
US-8293138-B2 Partially sulfonated polybenzimidazole based polymer, method for preparing the same, MEA for fuel cell using the polybenzimidazole based polymer and method for preparing the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-10-23 US disclosed
US-20120115050-A1 METHOD FOR IN-SITU PREPARATION OF POLYBENZIMIDAZOLE-BASED ELECTROLYTE MEMBRANE AND POLYBENZIMIDAZOLE-BASED ELECTROLYTE MEMBRANE PREPARED THEREBY KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2012-05-10 US disclosed
US-20110097642-A1 Polymer electrolyte membrane having high durability and method for producing the same ASAHI KASEI CHEMICALS CORPORATION (JP) 2011-04-28 US disclosed
US-7875392-B2 Fluorinated ion exchanger; casting polymer and solvent onto substrate ASAHI KASEI CHEMICALS CORPORATION (JP) 2011-01-25 US disclosed
US-7396615-B1 Method for production of polyelectrolyte membranes and fuel cell BASF FUEL CELL GMBH (DE) 2008-07-08 US disclosed