Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.75 |
| ▸ | HTR2C | P28335 | 1/20 | 0.75 |
| ▸ | AXL | P30530 | 1/20 | 0.75 |
| ▸ | HRH1 | P35367 | 1/20 | 0.75 |
| ▸ | HTR2B | P41595 | 1/20 | 0.75 |
| ▸ | HTR6 | P50406 | 1/20 | 0.75 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.75 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.75 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | CASP7 | P55210 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PHGDH | O43175 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14136364 | 0.87 | ADRB2 (0.77) | ADRB2ADRA2AHTR2CAXLHRH1 | |
| SCHEMBL2244546 | 0.86 | ADRB2 (1.00) | ADRB2ADRA2AHTR2CAXLHRH1 | |
| SCHEMBL13135657 | 0.86 | ADRB2 (0.75) | ADRB2ADRA2AHTR2CAXLHRH1 | |
| SCHEMBL10268283 | 0.86 | ADRB2 (0.75) | ADRB2ADRA2AHTR2CAXLHRH1 | |
| SCHEMBL6125222 | 0.84 | ADRB2 (0.72) | ADRB2ADRA2AHTR2CAXLHRH1 | |
| SCHEMBL14046596 | 0.84 | ADRB2 (0.72) | ADRB2ADRA2AHTR2CAXLHRH1 | |
| SCHEMBL6125250 | 0.84 | ADRB2 (0.72) | ADRB2ADRA2AHTR2CAXLHRH1 | |
| SCHEMBL13135656 | 0.83 | ADRB2 (0.70) | ADRB2ADRA2AHTR2CAXLHRH1 | |
| SCHEMBL1285720 | 0.83 | ADRB2 (0.70) | ADRB2ADRA2AHTR2CAXLHRH1 | |
| SCHEMBL14136366 | 0.76 | ADRB2 (0.61) | ADRB2ADRA2AHTR2CAXLHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930319-B1 | Proline derivatives and use thereof as drugs | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-20090017112-A1 | Compounds for Inhibiting Beta-Amyloid Production | ROSKAMP RESEARCH LLC (US) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090017112-A1 | Compounds for Inhibiting Beta-Amyloid Production | PSEN1, PSEN2, APP | ADRB2 1323/4885ADRA2A 792/4885HTR2C 3399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.