Biochanin

Biochanin

SCHEMBL61258

COc1ccc(-c2coc3cc(O)cc(O)c3c2=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 1.00
MAPT P10636 7/20 1.00
MEN1 O00255 6/20 1.00
KMT2A Q03164 6/20 1.00
SMN1; SMN2 Q16637 6/20 1.00
NPC1 O15118 6/20 1.00
ALDH1A1 P00352 6/20 1.00
CYP3A4 P08684 6/20 1.00
TP53 P04637 5/20 1.00
HPGD P15428 5/20 1.00
CYP2C9 P11712 4/20 1.00
CYP2C19 P33261 4/20 1.00
MAOA P21397 4/20 1.00
HSD17B10 Q99714 4/20 1.00
KDM4E B2RXH2 4/20 1.00
CYP2D6 P10635 3/20 1.00
NFKB1 P19838 3/20 1.00
NFKB2 Q00653 3/20 1.00
RELA Q04206 3/20 1.00
MAOB P27338 3/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biochanin SCHEMBL29410271 1.00 RAB9A (1.00) RAB9AMAPTMEN1KMT2ASMN1; SMN2
4',7-Dimethoxy-5-Hydroxygenistein SCHEMBL572108 0.93 RAB9A (1.00) RAB9AMAPTMEN1KMT2ASMN1; SMN2
Formononetin SCHEMBL6312014 0.91 MAPT (0.83) RAB9AMAPTMEN1KMT2ASMN1; SMN2
Formononetin SCHEMBL4223418 0.91 MAPT (0.83) RAB9AMAPTMEN1KMT2ASMN1; SMN2
Genistein SCHEMBL18241115 0.89 MEN1 (0.89) RAB9AMAPTMEN1KMT2ASMN1; SMN2
SCHEMBL12238015 0.88 SMN1; SMN2 (0.79) RAB9AMAPTMEN1KMT2ASMN1; SMN2
SCHEMBL12892701 0.88 RAB9A (0.81) RAB9AMAPTMEN1KMT2ASMN1; SMN2
SCHEMBL26145339 0.88 KDM4E (0.85) RAB9AMAPTMEN1KMT2ASMN1; SMN2
SCHEMBL13481416 0.88 MEN1 (0.79) RAB9AMAPTMEN1KMT2ASMN1; SMN2
Prunetin SCHEMBL29612430 0.88 ALDH2 (1.00) RAB9AMAPTMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6626 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122081128-A Lactobacillus rhamnosus and application thereof 2026-05-26 CN claimed
EP-4744663-A2 SKIN COMPOSITION Eaderm Co., Ltd. (JP) 2026-05-20 EP claimed
US-20260130395-A1 Water Dispersible Botanical Compositions AQUILA BLACK LTD (AU) 2026-05-14 US claimed
US-20260103663-A1 ANTIMICROBIAL MATERIALS AND NANOPARTICLES AND METHODS OF USE THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2026-04-16 US claimed
EP-3346842-B1 STABLE INOCULANT COMPOSITIONS AND METHODS FOR PRODUCING SAME NOVONESIS PLANT BIOSOLUTIONS AS (DK) 2026-03-25 EP claimed
EP-4701425-A1 SUNFLOWER OLEOSOME- AND PROTEIN-CONTAINING COMPOSITIONS FOR USE IN NUTRITIONAL FORMULATIONS Botaneco Inc. (CA) 2026-03-04 EP claimed
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 US claimed
US-12478605-B2 Biochanin a derivatives for treatment of BEST1-related retinopathies UNIVERSITÄT REGENSBURG (DE) 2025-11-25 US claimed
US-12474287-B2 Detection device and methods of use thereof AMULET, INC. (US) 2025-11-18 US claimed
EP-4125866-B1 BIOCHANIN A DERIVATIVES FOR TREATMENT OF BEST1-RELATED RETINOPATHIES UNIV REGENSBURG (DE) 2025-10-08 EP claimed
EP-0456808-A4 METHOD AND COMPOSITIONS FOR STIMULATING VESICULAR-ARBUSCULAR MYCORRHIZAL FUNGI UNIV MICHIGAN STATE (US) 1992-11-04 EP claimed
US-5125955-A Plant safening agents and growth regulators BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) 1992-06-30 US claimed
US-5085682-A Method and compositions for stimulating vesticular-arbuscular mycorrhizal fungi using isoflavonoids BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) 1992-02-04 US claimed
EP-0456808-A1 METHOD AND COMPOSITIONS FOR STIMULATING VESICULAR-ARBUSCULAR MYCORRHIZAL FUNGI. UNIV MICHIGAN STATE (US) 1991-11-21 EP claimed
CN-1052329-A Methods and compositions for stimulating vesicular-arbuscular mycorrhizal fungi UNIV MICHIGAN STATE (US) 1991-06-19 CN claimed
WO-1991007868-A1 METHOD AND COMPOSITIONS FOR STIMULATING VESICULAR-ARBUSCULAR MYCORRHIZAL FUNGI MICHIGAN STATE UNIVERSITY (US) 1991-06-13 WO claimed
US-5002603-A Stimulating plant growth with isoflavonoid BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) 1991-03-26 US claimed
EP-0024731-B1 A PHOTOSTABLE ANTHOCYANIC COLORANT COMPOSITION AND ITS USE IN A FOOD COMPOSITION THE COCA-COLA COMPANY (US) 1983-09-07 EP claimed
US-4285982-A MIXING WITH A FLAVONOL OR SULFONATED FLAVONOL; FLAVONOIDS; PLANT EXTRACTS; FOODS; DISCOLORATION INHIBITION THE COCA-COLA COMPANY (US) 1981-08-25 US claimed
EP-0024731-A1 A photostable anthocyanic colorant composition and its use in a food composition THE COCA-COLA COMPANY (US) 1981-03-11 EP claimed