Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.83 |
| ▸ | RAB9A | P51151 | 8/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.83 |
| ▸ | TP53 | P04637 | 7/20 | 0.83 |
| ▸ | HPGD | P15428 | 7/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.83 |
| ▸ | NPC1 | O15118 | 7/20 | 0.83 |
| ▸ | MEN1 | O00255 | 6/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.83 |
| ▸ | MAOA | P21397 | 6/20 | 0.83 |
| ▸ | MAOB | P27338 | 6/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.83 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.83 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.83 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.83 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.83 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.83 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.83 |
| ▸ | LMNA | P02545 | 3/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formononetin SCHEMBL6312014 | 1.00 | MAPT (0.83) | MAPTRAB9ASMN1; SMN2TP53HPGD | |
| Genistein SCHEMBL5801778 | 0.91 | SMN1; SMN2 (0.84) | MAPTRAB9ASMN1; SMN2TP53HPGD | |
| Formononetin SCHEMBL8416577 | 0.91 | KDM4E (0.97) | MAPTRAB9ASMN1; SMN2TP53HPGD | |
| Biochanin SCHEMBL61258 | 0.91 | RAB9A (1.00) | MAPTRAB9ASMN1; SMN2TP53HPGD | |
| Biochanin SCHEMBL29410271 | 0.91 | RAB9A (1.00) | MAPTRAB9ASMN1; SMN2TP53HPGD | |
| Formononetin SCHEMBL29361145 | 0.90 | KDM4E (1.00) | MAPTRAB9ASMN1; SMN2TP53HPGD | |
| Formononetin SCHEMBL62915 | 0.90 | KDM4E (1.00) | MAPTRAB9ASMN1; SMN2TP53HPGD | |
| Formononetin SCHEMBL15271536 | 0.90 | KDM4E (1.00) | MAPTRAB9ASMN1; SMN2TP53HPGD | |
| Formononetin SCHEMBL6638953 | 0.89 | KDM4E (0.97) | MAPTRAB9ASMN1; SMN2TP53HPGD | |
| Glycitein SCHEMBL8065644 | 0.89 | HDAC6 (0.78) | MAPTRAB9ASMN1; SMN2TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2135074-A2 | PHARMACEUTICAL PLATFORM TECHNOLOGY FOR THE DEVELOPMENT OF NATURAL PRODUCTS | 9898 Limited (CN) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008120105-A2 | PHARMACEUTICAL PLATFORM TECHNOLOGY FOR THE DEVELOPMENT OF NATURAL PRODUCTS | 9898 LIMITED (US) | 2008-10-09 | — | — | WO | disclosed |