Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.69 |
| ▸ | NAAA | Q02083 | 1/20 | 0.65 |
| ▸ | FAAH | O00519 | 4/20 | 0.61 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.55 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28005437 | 0.96 | CASP2 (0.69) | CASP2NAAAFAAHDNM1EPHX2 | |
| SCHEMBL29286451 | 0.93 | FAAH (0.66) | CASP2NAAAFAAHDNM1EPHX2 | |
| SCHEMBL23119693 | 0.91 | CASP2 (0.71) | CASP2NAAAFAAHDNM1EPHX2 | |
| Sulfuric Acid SCHEMBL28883481 | 0.90 | CASP2 (0.61) | CASP2NAAAFAAHDNM1EPHX2 | |
| SCHEMBL24073142 | 0.88 | CASP2 (0.80) | CASP2NAAAFAAHDNM1EPHX2 | |
| SCHEMBL24624954 | 0.87 | FAAH (0.68) | CASP2NAAAFAAHDNM1EPHX2 | |
| SCHEMBL24624692 | 0.87 | FAAH (0.68) | CASP2NAAAFAAHDNM1EPHX2 | |
| SCHEMBL24096028 | 0.87 | FAAH (0.68) | CASP2NAAAFAAHDNM1EPHX2 | |
| SCHEMBL4740424 | 0.87 | FAAH (0.68) | CASP2NAAAFAAHDNM1EPHX2 | |
| SCHEMBL19254127 | 0.87 | FAAH (0.57) | CASP2NAAAFAAHDNM1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2640700-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | Life Technologies Corporation (US) | 2013-09-25 | — | — | EP | disclosed |
| WO-2012068176-A1 | AMINE-CONTAINING TRANSFECTION REAGENTS AND METHODS FOR MAKING AND USING SAME | Life Technologies Corporation (US) | 2012-05-24 | — | — | WO | disclosed |