SCHEMBL612689

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL610541	0.97	TAAR1 (0.58)	TAAR1KCNH2LTA4HPLA2G2ADRD2
	SCHEMBL499757	0.93	MAOA (0.53)	TAAR1KCNH2HTR2ADRD2DRD4
	SCHEMBL611324	0.93	TAAR1 (0.62)	TAAR1KCNH2LTA4HHTR2APLA2G2A
	SCHEMBL2208245	0.92	TAAR1 (0.60)	TAAR1KCNH2LTA4HHTR2APLA2G2A
	SCHEMBL29818724	0.92	TAAR1 (0.60)	TAAR1KCNH2LTA4HHTR2APLA2G2A
	SCHEMBL17040303	0.90	TAAR1 (0.58)	TAAR1KCNH2LTA4HHTR2APLA2G2A
	SCHEMBL2207165	0.90	MAOA (0.53)	TAAR1KCNH2DRD2DRD4DRD3
	SCHEMBL19291779	0.89	TAAR1 (0.56)	TAAR1KCNH2LTA4HHTR2APLA2G2A
	SCHEMBL2208821	0.89	MAOA (0.52)	TAAR1KCNH2DRD2DRD4DRD3
	SCHEMBL20332570	0.87	KCNA3 (0.53)	TAAR1KCNH2LTA4HDRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.