Serine

Serine

SCHEMBL6128091

C=CC=CC(C=Cc1ccccc1)C(=C)C(=O)OC.N[C@@H](CO)C(=O)O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 8/20 0.38
GRIK2 Q13002 7/20 0.36
LMNA P02545 1/20 0.34
CYP3A4 P08684 1/20 0.34
GRIK3 Q13003 1/20 0.34
CYP1A2 P05177 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KIF11 P52732 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CNR2 P34972 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34195 0.89 CYP3A4 (0.41) LMNACYP3A4CYP1A2TDP1MEN1
Vinyl Chloride SCHEMBL9625391 0.85 LMNA (0.39) LMNACYP3A4CYP1A2TDP1MEN1
Acrylonitrile SCHEMBL9249811 0.82 LMNA (0.37) LMNACYP3A4CYP1A2TDP1MEN1
Styrene SCHEMBL1069591 0.80 LMNA (0.35) LMNACYP3A4CYP1A2TDP1MEN1
SCHEMBL8675986 0.78 MEN1 (0.47) LMNACYP3A4MEN1KMT2A
Styrene SCHEMBL6128092 0.78 GRIK1 (0.39) GRIK1GRIK2GRIK3KIF11
Acrylonitrile SCHEMBL8734346 0.77 LMNA (0.38) LMNACYP3A4CYP1A2TDP1
SCHEMBL6686282 0.76 MEN1 (0.42) LMNACYP3A4CYP1A2MEN1KMT2A
SCHEMBL5418266 0.75 HDAC3 (0.45) LMNACYP3A4CYP1A2TDP1MEN1
Serine SCHEMBL3811629 0.75 GRIK1 (0.52) GRIK1GRIK2LMNACYP3A4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463339-A1 POLYESTER RESIN COMPOSITION Mitsubishi Gas Chemical Company, Inc. (JP) 2012-06-13 EP claimed
US-20120128984-A1 POLYESTER RESIN COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-05-24 US claimed
EP-2463339-A1 POLYESTER RESIN COMPOSITION Mitsubishi Gas Chemical Company, Inc. (JP) 2012-06-13 EP disclosed
US-20120128984-A1 POLYESTER RESIN COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-05-24 US disclosed