Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CMA1 | P23946 | 2/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylonitrile SCHEMBL9249811 | 0.97 | LMNA (0.37) | LMNACYP3A4TDP1APPALDH1A1 | |
| Acrylonitrile SCHEMBL8734346 | 0.91 | LMNA (0.38) | LMNACYP3A4TDP1APPALDH1A1 | |
| SCHEMBL34195 | 0.90 | CYP3A4 (0.41) | LMNACYP3A4TDP1ALDH1A1CYP1A2 | |
| Styrene SCHEMBL7727957 | 0.88 | ALDH1A1 (0.33) | LMNACYP3A4APPALDH1A1TSHR | |
| Butadiene SCHEMBL11122770 | 0.86 | TDP1 (0.36) | LMNACYP3A4TDP1APPALDH1A1 | |
| Vinyl Chloride SCHEMBL9625391 | 0.86 | LMNA (0.39) | LMNACYP3A4TDP1ALDH1A1CYP1A2 | |
| SCHEMBL544657 | 0.83 | TDP1 (0.38) | LMNACYP3A4TDP1APPALDH1A1 | |
| Acrylonitrile SCHEMBL29268884 | 0.80 | ALDH1A1 (0.34) | LMNATDP1ALDH1A1KDM4EMAPT | |
| Serine SCHEMBL6128091 | 0.80 | GRIK1 (0.38) | LMNACYP3A4TDP1CYP1A2MEN1 | |
| Styrene SCHEMBL1069594 | 0.79 | ALDH1A1 (0.42) | LMNAALDH1A1HTTKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034866-B2 | Polyester, polycarbonate, impact modifier, reinforcing filler, fibrillated fluoropolymer, and antioxidants, mold release agents, colorants, quenchers, or stabilizers; power tool housings; higher modulus, improved ductility, impact strength, melt processability, molding speed; cost efficiency | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-10-11 | — | — | US | disclosed |
| EP-2276809-A1 | POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM | SABIC Innovative Plastics IP B.V. (NL) | 2011-01-26 | — | — | EP | disclosed |
| WO-2009137626-A1 | POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-11-12 | — | — | WO | disclosed |
| US-20080242789-A1 | Polymer Compositions, Method of Manufacture, and Articles Formed Therefrom | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-10-02 | — | — | US | disclosed |