SCHEMBL612883

SCHEMBL612883

COc1cccc(Br)c1.[MgH2]

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.59
ACHE P22303 1/20 0.54
ALDH1A1 P00352 2/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CYP3A4 P08684 1/20 0.52
LMNA P02545 1/20 0.47
HPGD P15428 1/20 0.47
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
ENPP2 Q13822 1/20 0.47
MAPK1 P28482 1/20 0.46
CYP1A2 P05177 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
RECQL P46063 1/20 0.46
CA4 P22748 1/20 0.46
CHRM5 P08912 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL5349904 0.98 MAOB (0.58) MAOBACHEALDH1A1CA1CA2
SCHEMBL8008145 0.98
SCHEMBL29374752 0.98
SCHEMBL156145 0.98
Ammonia Solution, Strong SCHEMBL27895478 0.95 MAOB (0.59) MAOBACHEALDH1A1CA1CA2
Bromide SCHEMBL4665378 0.93 MAOB (0.58) MAOBACHEALDH1A1CA1CA2
Hydrochloric Acid SCHEMBL27560881 0.93 MAOB (0.58) MAOBACHEALDH1A1CA1CA2
Cyanide SCHEMBL27586511 0.91 MAOB (0.56) MAOBACHEALDH1A1CA1CA2
Ethane SCHEMBL27513340 0.91 MAOB (0.56) MAOBACHEALDH1A1CA1CA2
SCHEMBL27580985 0.87 MAOB (0.57) MAOBACHEALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 365 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115260043-B Synthesis method of meta-hydroxylamine bitartrate 海南长春花药业有限公司 2024-03-22 CN claimed
CN-115701422-A Preparation method of KGP94 中国科学院昆明植物研究所 2023-02-10 CN claimed
CN-115260043-A Synthesis method of meta-hydroxylamine bitartrate 海南长春花药业有限公司 2022-11-01 CN claimed
CN-114436790-A Synthesis method of 6-methoxy-1-tetralone 浙江仙居君业药业有限公司 2022-05-06 CN claimed
CN-101265201-B Method for synthesizing tramadol hydrochloride UNIV ZHEJIANG TECHNOLOGY 2011-11-23 CN claimed
CN-100548950-C Process for preparing esters and ethers of probucol and derivatives thereof ATHEROGENICS INC (US) 2009-10-14 CN claimed
US-7470816-B2 Tramadol recovery process IPAC LABORATORIES LIMITED (IN) 2008-12-30 US claimed
CN-101265201-A Method for synthesizing tramadol hydrochloride UNIV ZHEJIANG TECHNOLOGY (CN) 2008-09-17 CN claimed
US-20070112074-A1 Tramadol recovery process IPCA LABORATORIES LIMITED (IN) 2007-05-17 US claimed
EP-1785412-A1 Tramadol recovery process IPCA Laboratories Limited (IN) 2007-05-16 EP claimed
CN-1759084-A Process for preparing esters and ethers of probucol and derivatives thereof ATHEROGENICS INC (US) 2006-04-12 CN claimed
WO-2025137310-A1 CRYSTALLINE GPR40 AGONIST AND METHODS OF MAKING KALLYOPE, INC. (US) 2025-06-26 WO disclosed
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
CN-118955473-A Difunctional compounds for degrading BTK via the ubiquitin proteasome pathway 紐力克斯治疗公司 2024-11-15 CN disclosed
CN-118382610-A DHODH inhibitors containing carboxylic acid bioisosteres 埃慕尼克股份公司 2024-07-23 CN disclosed
US-4387097-A Morpholines JOHN WYETH AND BROTHER LIMITED (GB) 1983-06-07 US disclosed
EP-0061712-A1 Antiinflammatory and/or analgesic 1,8-dihydro (or 3,8-dihydro)-8-aryl-2-((substituted)thio)-indeno(1,2-)imidazoles and their corresponding sulfoxides and sulfones E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-10-06 EP disclosed
EP-0061899-A1 Morpholines JOHN WYETH & BROTHER LIMITED (GB) 1982-10-06 EP disclosed
US-4301164-A FOR USE AS ANTIULCER AGENTS, HYPOTENSIVE AGENTS, ANTITHROMBOSIC AGENTS TORAY INDUSTRIES, INC. (JP) 1981-11-17 US disclosed
EP-0024943-A1 5,6,7-Trinor-4,8-inter-m-phenylene PGI2 derivatives and pharmaceutical compositions containing them TORAY INDUSTRIES, INC. (JP) 1981-03-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070112074-A1 Tramadol recovery process TRAM1, OPRK1, SLC6A6 MAOB 921/4885ACHE 894/4885ALDH1A1 1251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.