SCHEMBL6129137

SCHEMBL6129137

C=CC(CC)NC(=O)NC(C=C)CC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
TSHR P16473 3/20 0.34
FOLH1 Q04609 3/20 0.34
NAALAD2 Q9Y3Q0 3/20 0.34
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
LMNA P02545 1/20 0.32
PKM P14618 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
RIMKLA Q8IXN7 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
BLM P54132 1/20 0.31
SLC6A3 Q01959 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MMP1 P03956 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23748263 0.88
SCHEMBL11296644 0.84
SCHEMBL11525715 0.82 CYP2C9 (0.43) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL23009033 0.80 SMN1; SMN2 (0.33) ALDH1A1LMNASMN1; SMN2L3MBTL1
SCHEMBL19446848 0.79 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL10907118 0.74
SCHEMBL2900790 0.74 CTSK (0.51) CA1CA2
SCHEMBL12635207 0.74 CTSK (0.51) CA1CA2
SCHEMBL27346455 0.73 PSMB5 (0.32) TSHR
SCHEMBL9501579 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2670519-B1 COMPOSITE MATERIAL PORVAIR FILTRATION GROUP LTD (GB) 2021-09-22 EP disclosed
US-20200346147-A1 USE OF POLYMERS AS FILTERING AIDS AND/OR STABILIZERS BASF SE (DE) 2020-11-05 US disclosed
US-10744434-B2 Use of polymers comprising thermoplastic polymers as filtration aids and/or stabilising agent BASF SE (DE) 2020-08-18 US disclosed
US-9215891-B2 Composite material PORVAIR FILTRATION GROUP LIMITED (GB) 2015-12-22 US disclosed
EP-2670519-A1 COMPOSITE MATERIAL Porvair Filtration Group Limited (GB) 2013-12-11 EP disclosed
US-20130323383-A1 COMPOSITE MATERIAL PORVAIR FILTRATION GROUP LIMITED (GB) 2013-12-05 US disclosed
WO-2012104637-A1 COMPOSITE MATERIAL PORVAIR FILTRATION GROUP LIMITED (GB) 2012-08-09 WO disclosed
US-20050145579-A1 Use of polymers comprising thermoplastic polymers as filtration aids and/or stabilising agent BASF SE (DE) 2005-07-07 US disclosed
US-20040094486-A1 Use of polymers as filtering aids and/or stabilizers BASF SE (DE) 2004-05-20 US disclosed