Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6129169 | 0.87 | ALDH1A1 (0.36) | ALDH1A1TSHR | |
| SCHEMBL9434593 | 0.79 | TLR8 (0.33) | — | |
| SCHEMBL720164 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHR | |
| SCHEMBL9626812 | 0.78 | TSHR (0.39) | TSHR | |
| SCHEMBL12697346 | 0.77 | — | — | |
| SCHEMBL11045961 | 0.77 | CDK1 (0.31) | — | |
| Ether SCHEMBL9062191 | 0.77 | TSHR (0.43) | ALDH1A1TSHRTDP1 | |
| SCHEMBL13428354 | 0.77 | — | — | |
| SCHEMBL6175842 | 0.74 | — | — | |
| SCHEMBL21587465 | 0.74 | TSHR (0.41) | ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2429568-B1 | MACROCYCLIC COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS | ENANTA PHARM INC (US) | 2016-08-17 | — | — | EP | disclosed |
| US-20050288430-A1 | Polyurethane dispersions with high acid content | BAYER POLYMERS LLC | 2005-12-29 | — | — | US | disclosed |
| US-20050288431-A1 | Polyurethane dispersion prepared from a high acid functional polyester | BAYER MATERIALSCIENCE LLC | 2005-12-29 | — | — | US | disclosed |
| EP-1609808-A2 | Polyurethane dispersion prepared from a high acid functional polyester | Bayer MaterialScience LLC (US) | 2005-12-28 | — | — | EP | disclosed |
| EP-1609809-A1 | Polyurethane dispersions with high acid content | Bayer MaterialScience LLC (US) | 2005-12-28 | — | — | EP | disclosed |
| EP-1607424-A1 | A method of direct-to-metal coating | Bayer MaterialScience LLC (US) | 2005-12-21 | — | — | EP | disclosed |
| US-20050277732-A1 | Two-component coating composition | COVESTRO LLC | 2005-12-15 | — | — | US | disclosed |
| EP-1311571-B1 | AQUEOUS DISPERSIONS OF PYRAZOLE BLOCKED POLYISOCYANATES AND COATINGS PREPARED THEREFROM | BAYER MATERIALSCIENCE AG (DE) | 2005-08-17 | — | — | EP | disclosed |
| EP-0444454-B2 | Air-drying polyurethane resins, their preparation and use | SURFACE SPECIALTIES GERMANY GM (DE) | 2004-04-28 | — | — | EP | disclosed |
| EP-1311571-A2 | AQUEOUS DISPERSIONS | Bayer Aktiengesellschaft (DE) | 2003-05-21 | — | — | EP | disclosed |
| EP-0444454-B1 | Air-drying polyurethane resins, their preparation and use | HOECHST AG (DE) | 1994-11-30 | — | — | EP | disclosed |
| EP-0612779-A2 | Acid modified polyesters and their use in stove enamels | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-08-31 | — | — | EP | disclosed |
| EP-0355682-B1 | Use of polyurethane resins in aqueous filler compositions | HOECHST AG (DE) | 1994-06-15 | — | — | EP | disclosed |
| EP-0436941-B1 | Aqueous coating composition, its preparation and utilization | HOECHST AG (DE) | 1994-04-13 | — | — | EP | disclosed |
| EP-0548728-A1 | Filler composition based on polyester | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-30 | — | — | EP | disclosed |
| EP-0444454-A2 | Air-drying polyurethane resins, their preparation and use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-04 | — | — | EP | disclosed |
| EP-0436941-A1 | Aqueous coating composition, its preparation and utilization | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-17 | — | — | EP | disclosed |
| US-4958026-A | HYPOTENSIVE AGENTS | SCHERING AKTIENGESLLSCHAFT (DE) | 1990-09-18 | — | — | US | disclosed |
| EP-0355682-A2 | Use of polyurethane resins in aqueous filler compositions | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-28 | — | — | EP | disclosed |
| US-4137328-A | CONGESTIVE HEART FAILURE | PFIZER INC. (US) | 1979-01-30 | — | — | US | disclosed |