SCHEMBL120459

SCHEMBL120459

CC1=C(N2CCCC2)C(=O)CC1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.40
L3MBTL1 Q9Y468 2/20 0.34
ALDH1A1 P00352 5/20 0.33
POLB P06746 2/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
APAF1 O14727 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
ALDH1A3 P47895 2/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
GAA P10253 1/20 0.31
GPR55 Q9Y2T6 1/20 0.30
BRD4 O60885 1/20 0.30
BRD2 P25440 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6129238 0.98 SMN1; SMN2 (0.43) SMN1; SMN2L3MBTL1ALDH1A1POLBMAPT
SCHEMBL4582486 0.89 SMN1; SMN2 (0.36) SMN1; SMN2L3MBTL1ALDH1A1POLBMAPT
SCHEMBL1674760 0.74 SMN1; SMN2 (0.50) SMN1; SMN2L3MBTL1ALDH1A1POLBMAPT
SCHEMBL6129225 0.73 SMN1; SMN2 (0.53) SMN1; SMN2L3MBTL1GAA
SCHEMBL161507 0.72
SCHEMBL24415343 0.71 SMN1; SMN2 (0.56) SMN1; SMN2L3MBTL1ALDH1A1POLBMAPT
SCHEMBL6129223 0.71 MAPT (0.44) SMN1; SMN2L3MBTL1ALDH1A1POLBMAPT
SCHEMBL10446742 0.70 APAF1 (0.39) SMN1; SMN2L3MBTL1ALDH1A1POLBMAPT
SCHEMBL469465 0.70 TYR (0.43) SMN1; SMN2L3MBTL1ALDH1A1POLBMAPT
SCHEMBL247419 0.70 L3MBTL1 (0.36) SMN1; SMN2L3MBTL1ALDH1A1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028562-A1 FLAVORED POROUS MATERIAL FOR FLAVORED BEVERAGE PRODUCTION DANSTAR FERMENT AG (CH) 2026-01-29 US claimed
EP-4622621-A1 AN ACTIVE COMPOSITION COMPRISING RETINOL Symrise AG (DE) 2025-10-01 EP claimed
EP-4557970-A1 FLAVORED POROUS MATERIAL FOR FLAVORED BEVERAGE PRODUCTION Danstar Ferment AG (CH) 2025-05-28 EP claimed
EP-4472606-A1 COMPOSITIONS (III) Symrise AG (DE) 2024-12-11 EP claimed
CN-118829416-A Composition (III) 西姆莱斯股份公司 2024-10-22 CN claimed
EP-4429465-A1 COMPOSITIONS COMPRISING TRPM8 AGONISTIC COOLING AGENTS Symrise AG (DE) 2024-09-18 EP claimed
WO-2024110515-A1 AN ACTIVE COMPOSITION COMPRISING RETINOL SYMRISE AG (DE) 2024-05-30 WO claimed
EP-4351667-A1 COMPOSITIONS FOR FIGHTING MALODORS Symrise AG (DE) 2024-04-17 EP claimed
CN-117813077-A Composition and method for producing the same 西姆莱斯股份公司 2024-04-02 CN claimed
CN-117615798-A Composition for combating malodour 西姆莱斯股份公司 2024-02-27 CN claimed
WO-2015158677-A1 HOMOVANILLIC ESTER, MORE PARTICULARLY FOR ACHIEVING AN IMPRESSION OF HEAT AND/OR SPICINESS SYMRISE AG (DE) 2015-10-22 WO claimed
EP-2932858-A1 Homovanillic acid esters, in particular for achieving an impression of heat and/or spiciness Symrise AG (DE) 2015-10-21 EP claimed
EP-2008530-B1 Aroma composition for reducing or suppressing unwanted bitter and astringent impressions SYMRISE AG (DE) 2011-01-19 EP claimed
EP-2008530-A1 Aroma composition for reducing or suppressing unwanted bitter and astringent impressions Symrise GmbH & Co. KG (DE) 2008-12-31 EP claimed
US-20080317923-A1 AROMA COMPOSITION FOR REDUCING OR SUPPRESSING AN UNDESIRED BITTER, ASTRINGENT IMPRESSION SYMRISE GMBH & CO. KG (DE) 2008-12-25 US claimed
US-20050000529-A1 Method and compositions for imparting cooling effect to tobacco products VECTOR TOBACCO INC. 2005-01-06 US claimed
EP-1455609-A2 METHOD AND COMPOSITIONS FOR IMPARTING COOLING EFFECT TO TOBACCO PRODUCTS Vector Tobacco Inc. (US) 2004-09-15 EP claimed
US-20040052828-A1 Consumable product including consumable component and alpha-keto enamine derivatives NESTEC S.A. (CH) 2004-03-18 US claimed
WO-2003053176-A2 METHOD AND COMPOSITIONS FOR IMPARTING COOLING EFFECT TO TOBACCO PRODUCTS VECTOR TOBACCO INC. (US) 2003-07-03 WO claimed
US-20020022039-A1 Method of using alpha-keto enamine derivatives as ingredients and products incorporating same NESTEC S.A. (CH) 2002-02-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040052828-A1 Consumable product including consumable component and alpha-keto enamine derivatives PKN2, OPRD1, PKN1 SMN1; SMN2 2021/4885L3MBTL1 3770/4885ALDH1A1 484/4885
US-20020022039-A1 Method of using alpha-keto enamine derivatives as ingredients and products incorporating same ECH1, KMO, PKN1 SMN1; SMN2 3101/4885L3MBTL1 3305/4885ALDH1A1 840/4885
US-20260028562-A1 FLAVORED POROUS MATERIAL FOR FLAVORED BEVERAGE PRODUCTION CD69, SORD, TAS2R13 SMN1; SMN2 1256/4885L3MBTL1 4141/4885ALDH1A1 93/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.