Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.56 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.56 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.56 |
| ▸ | CDK1 | P06493 | 1/20 | 0.56 |
| ▸ | CDK4 | P11802 | 1/20 | 0.56 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.56 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.56 |
| ▸ | CCND1 | P24385 | 1/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | CDK7 | P50613 | 1/20 | 0.56 |
| ▸ | CDK9 | P50750 | 1/20 | 0.56 |
| ▸ | CCNH | P51946 | 1/20 | 0.56 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.56 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.56 |
| ▸ | PLAU | P00749 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006324 | 0.98 | NPC1 (0.59) | NPC1RAB9AGAAL3MBTL1CCNT1 | |
| SCHEMBL2003135 | 0.98 | NPC1 (0.59) | NPC1RAB9AGAAL3MBTL1CCNT1 | |
| SCHEMBL11858508 | 0.82 | CCNT1 (0.64) | NPC1RAB9AL3MBTL1CCNT1CCNB2 | |
| SCHEMBL6575341 | 0.80 | NPC1 (0.54) | NPC1RAB9AL3MBTL1CCNT1CCNB2 | |
| SCHEMBL6575346 | 0.80 | NPC1 (0.54) | NPC1RAB9AL3MBTL1CCNT1CCNB2 | |
| SCHEMBL11456229 | 0.79 | CCNT1 (0.54) | NPC1RAB9AL3MBTL1CCNT1CCNB2 | |
| SCHEMBL11456230 | 0.79 | CCNT1 (0.54) | NPC1RAB9AL3MBTL1CCNT1CCNB2 | |
| SCHEMBL9658763 | 0.79 | CCNT1 (0.54) | NPC1RAB9AGAAL3MBTL1CCNT1 | |
| SCHEMBL9658765 | 0.79 | CCNT1 (0.54) | NPC1RAB9AGAAL3MBTL1CCNT1 | |
| SCHEMBL1263553 | 0.78 | PLAU (0.53) | NPC1RAB9AL3MBTL1CCNT1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864347-B2 | Nonlinear optical chiral compounds and devices incorporating same | KVH INDUSTRIES, INC. (US) | 2005-03-08 | — | — | US | disclosed |
| US-20030161605-A1 | Nonlinear optical chiral compounds and devices incorporating same | KVH INDUSTRIES, INC. | 2003-08-28 | — | — | US | disclosed |
| WO-2003003112-A1 | NONLINEAR OPTICAL CHIRAL COMPOUNDS AND DEVICES INCORPORATING SAME | KVH INDUSTRIES, INC. (US) | 2003-01-09 | — | — | WO | disclosed |
| US-6288206-B1 | MIXED WITH DYE; HEAT RESISTANCE, STABILITY; ELECTROOPTICS; | MOLECULAR OPTOELECTRONICS CORPORATION | 2001-09-11 | — | — | US | disclosed |
| WO-2000054103-A1 | CHIRAL POLYMER COMPOSITIONS EXHIBITING NONLINEAR OPTICAL PROPERTIES | MOLECULAR OPTOELECTRONICS CORPORATION (US) | 2000-09-14 | — | — | WO | disclosed |