SCHEMBL2003135

SCHEMBL2003135

Nc1ccccc1/N=N/c1ccccc1[N+](=O)[O-]

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.59
RAB9A P51151 3/20 0.59
GAA P10253 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
CCNT1 O60563 1/20 0.57
CCNB2 O95067 1/20 0.57
CCNE2 O96020 1/20 0.57
CDK1 P06493 1/20 0.57
CDK4 P11802 1/20 0.57
CCNB1 P14635 1/20 0.57
CCNA2 P20248 1/20 0.57
CCND1 P24385 1/20 0.57
CCNE1 P24864 1/20 0.57
CDK2 P24941 1/20 0.57
CDK7 P50613 1/20 0.57
CDK9 P50750 1/20 0.57
CCNH P51946 1/20 0.57
CCNA1 P78396 1/20 0.57
CCNB3 Q8WWL7 1/20 0.57
PLAU P00749 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9006324 1.00 NPC1 (0.59) NPC1RAB9AGAAL3MBTL1CCNT1
SCHEMBL6129305 0.98 NPC1 (0.57) NPC1RAB9AGAAL3MBTL1CCNT1
SCHEMBL11858508 0.84 CCNT1 (0.64) NPC1RAB9AL3MBTL1CCNT1CCNB2
SCHEMBL6575341 0.82 NPC1 (0.54) NPC1RAB9AL3MBTL1CCNT1CCNB2
SCHEMBL6575346 0.82 NPC1 (0.54) NPC1RAB9AL3MBTL1CCNT1CCNB2
SCHEMBL11456229 0.81 CCNT1 (0.54) NPC1RAB9AL3MBTL1CCNT1CCNB2
SCHEMBL11456230 0.81 CCNT1 (0.54) NPC1RAB9AL3MBTL1CCNT1CCNB2
SCHEMBL9658763 0.81 CCNT1 (0.54) NPC1RAB9AGAAL3MBTL1CCNT1
SCHEMBL9658765 0.81 CCNT1 (0.54) NPC1RAB9AGAAL3MBTL1CCNT1
SCHEMBL1263553 0.79 PLAU (0.53) NPC1RAB9AL3MBTL1CCNT1CCNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2846848-B1 OPHTHALMIC VISCOELASTIC DEVICE ZEISS CARL MEDITEC AG (DE) 2018-03-07 EP claimed
US-20150119356-A1 Ophthalmic Viscoelastic Device CARL ZEISS MEDITEC AG (DE) 2015-04-30 US claimed
EP-2846848-A1 OPHTHALMIC VISCOELASTIC DEVICE Carl Zeiss Meditec AG (DE) 2015-03-18 EP claimed
WO-2013167632-A1 OPHTHALMIC VISCOELASTIC DEVICE CARL ZEISS MEDITEC AG (DE) 2013-11-14 WO claimed
EP-0524637-B1 Mixture of dyes for cyan dye donor for thermal color proofing EASTMAN KODAK CO (US) 1996-03-06 EP claimed
EP-0524637-A1 Mixture of dyes for cyan dye donor for thermal color proofing EASTMAN KODAK COMPANY (US) 1993-01-27 EP claimed
US-5177052-A MIXTURE OF DYES FOR CYAN DYE DONOR FOR THERMAL COLOR PROOFING EASTMAN KODAK COMPANY (US) 1993-01-05 US claimed
EP-2846848-B1 OPHTHALMIC VISCOELASTIC DEVICE ZEISS CARL MEDITEC AG (DE) 2018-03-07 EP disclosed
US-20150119356-A1 Ophthalmic Viscoelastic Device CARL ZEISS MEDITEC AG (DE) 2015-04-30 US disclosed
EP-2846848-A1 OPHTHALMIC VISCOELASTIC DEVICE Carl Zeiss Meditec AG (DE) 2015-03-18 EP disclosed
WO-2013167632-A1 OPHTHALMIC VISCOELASTIC DEVICE CARL ZEISS MEDITEC AG (DE) 2013-11-14 WO disclosed
WO-2013020917-A1 Ophthalmologic composition comprising an aqueous solution of at least one viscoelastic polysaccharide CARL ZEISS MEDITEC AG (DE) 2013-02-14 WO disclosed
US-7960320-B2 Dispersant viscosity modifiers containing aromatic amines THE LUBRIZOL CORPORATION (US) 2011-06-14 US disclosed
US-5168094-A Thermal printing EASTMAN KODAK COMPANY (US) 1992-12-01 US disclosed
EP-0511625-A1 Mixture of yellow and cyan dyes to form a green hue for color filter array element EASTMAN KODAK COMPANY (US) 1992-11-04 EP disclosed
US-5147844-A Polymeric image receiving layer, having a thermally transferred image of a repeating pattern thereon, on a support EASTMAN KODAK COMPANY (US) 1992-09-15 US disclosed
EP-0486995-A1 Mixture of dyes for magenta dye donor for thermal color proofing EASTMAN KODAK COMPANY (US) 1992-05-27 EP disclosed
EP-0483800-A1 Mixture of dyes for magenta dye donor for thermal color proofing EASTMAN KODAK COMPANY (US) 1992-05-06 EP disclosed
US-5061676-A Mixture of dyes for magenta dye donor for thermal color proofing EASTMAN KODAK COMPANY (US) 1991-10-29 US disclosed
US-5023229-A Mixture of dyes for magenta dye donor for thermal color proofing EASTMAN KODAK COMPANY (US) 1991-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150119356-A1 Ophthalmic Viscoelastic Device UACA, ICAM1, VIM NPC1 4214/4885RAB9A 3139/4885GAA 2851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.