Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.51 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.51 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | CDK4 | P11802 | 1/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.51 |
| ▸ | CCND1 | P24385 | 1/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | CDK7 | P50613 | 1/20 | 0.51 |
| ▸ | CDK9 | P50750 | 1/20 | 0.51 |
| ▸ | CCNH | P51946 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575341 | 1.00 | NPC1 (0.54) | NPC1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL2003135 | 0.82 | NPC1 (0.59) | NPC1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL9006324 | 0.82 | NPC1 (0.59) | NPC1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL12957569 | 0.81 | CTSB (0.60) | NPC1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL6129305 | 0.80 | NPC1 (0.57) | NPC1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL6579230 | 0.80 | MEN1 (0.66) | NPC1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL6579225 | 0.80 | MEN1 (0.66) | NPC1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL8653147 | 0.79 | TDP1 (0.80) | NPC1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL13330237 | 0.78 | TDP1 (0.53) | NPC1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL9658765 | 0.78 | CCNT1 (0.54) | NPC1MEN1MAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699975-B2 | OLIGONUCLEOTIDE FOR USE AS TOOL IN THE DETECTION OF PREFERENTIAL COMPOUNDS IN SOLUTION | EPOCH BIOSCIENCES, INC. | 2004-03-02 | — | — | US | claimed |