Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12386663 | 0.91 | TSHR (0.50) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL10892751 | 0.91 | TSHR (0.50) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL10890546 | 0.91 | TSHR (0.50) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL19201285 | 0.87 | THRB (0.44) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL12430619 | 0.87 | THRB (0.44) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL9767720 | 0.84 | TSHR (0.59) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL19215618 | 0.81 | THRB (0.41) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL10892651 | 0.80 | THRB (0.47) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL2784396 | 0.80 | THRB (0.47) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL29380620 | 0.80 | THRB (0.47) | THRBTSHRALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124578-A4 | NOVEL IMMUNOADJUVANTS | AVANT IMMUNOTHERAPEUTICS INC (US) | 2005-01-19 | — | — | EP | disclosed |
| EP-1124578-A1 | NOVEL IMMUNOADJUVANTS | Avant Immunotherapeutics, Inc. (US) | 2001-08-22 | — | — | EP | disclosed |
| US-6261573-B1 | MIXTURE OF ANTIGEN, WATER SOLUBLE POLYMER AND AMPHIPHILIC COMPOUNDS | AVANT IMMUNOTHERAPEUTICS, INC. | 2001-07-17 | — | — | US | disclosed |
| WO-2000025815-A1 | NOVEL IMMUNOADJUVANTS | AVANT IMMUNOTHERAPEUTICS, INC. (US) | 2000-05-11 | — | — | WO | disclosed |