Pyrophosphoric Acid

Pyrophosphoric Acid

SCHEMBL6129657

CC(C)C=CO.O=P(O)(O)OP(=O)(O)O

nearest known ligand 0.48

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Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.48
BLM P54132 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
BTN3A1 O00481 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL6129660 0.85 LAP3 (0.32)
SCHEMBL347561 0.76
SCHEMBL346816 0.76
Pyrophosphoric Acid SCHEMBL27846493 0.75 FDPS (0.53) FDPSBLMTDP1BTN3A1
Pyrophosphoric Acid SCHEMBL28110229 0.73 FDPS (0.67) FDPSBLMTDP1BTN3A1
Pyrophosphoric Acid SCHEMBL28489286 0.72 FDPS (0.91) FDPSBLMTDP1BTN3A1
Pyrophosphoric Acid SCHEMBL5083772 0.71 FDPS (0.62) FDPSBLMTDP1BTN3A1
Pyrophosphoric Acid SCHEMBL6911209 0.70 FDPS (0.71) FDPSBLMTDP1BTN3A1
Pyrophosphoric Acid SCHEMBL3910021 0.69 FDPS (0.83) FDPSBLMTDP1BTN3A1
Pyrophosphoric Acid SCHEMBL28456752 0.69 FDPS (0.83) FDPSBLMTDP1BTN3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118121703-A Specific inhibitor of targeted GGPS1 and application thereof 中国医学科学院皮肤病医院(中国医学科学院皮肤病研究所) 2024-06-04 CN disclosed
US-11660961-B2 Host cells and methods for producing isopentenol from mevalonate THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-05-30 US disclosed
US-11312981-B2 Carotenoid and amino acid biosynthesis using recombinant corynebacterium glutamicum UNIVERSITÄT BIELEFELD (DE) 2022-04-26 US disclosed
US-20210023947-A1 Novel Host Cells and Methods for Producing Isopentenol from Mevalonate UNITED STATES DEPARTMENT OF ENERGY 2021-01-28 US disclosed
US-10814724-B2 Host cells and methods for producing isopentenol from mevalonate THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-10-27 US disclosed
US-20190248239-A1 Novel Host Cells and Methods for Producing Isopentenol from Mevalonate THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-08-15 US disclosed
US-10273506-B2 Host cells and methods for producing isopentenol from mevalonate THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-04-30 US disclosed
US-20180080052-A1 Novel Host Cells and Methods for Producing Isopentenol from Mevalonate UNITED STATES DEPARTMENT OF ENERGY 2018-03-22 US disclosed
WO-2016134381-A1 NOVEL HOST CELLS AND METHODS FOR PRODUCING ISOPENTENOL FROM MEVALONATE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-08-25 WO disclosed
EP-1228238-A4 NUCLEIC ACID MOLECULES ENCODING ISOPENTENYL MONOPHOSPHATE KINASE, AND METHODS OF USE UNIV WASHINGTON (US) 2005-05-25 EP disclosed
EP-1228238-A1 NUCLEIC ACID MOLECULES ENCODING ISOPENTENYL MONOPHOSPHATE KINASE, AND METHODS OF USE WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) 2002-08-07 EP disclosed
US-6235514-B1 NUCLEOTIDE SEQUENCES; FOR RECOMBINANT PRODUCTION AND TRANSGENIC PLANTS AND ORGANISMS WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION 2001-05-22 US disclosed
WO-2001032907-A1 NUCLEIC ACID MOLECULES ENCODING ISOPENTENYL MONOPHOSPHATE KINASE, AND METHODS OF USE WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) 2001-05-10 WO disclosed