Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 5/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSH | P09668 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5669104 | 0.84 | PNMT (0.38) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL6676496 | 0.79 | PNMT (0.44) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL4462321 | 0.78 | NPC1 (0.41) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL28565431 | 0.78 | PNMT (0.43) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL4556624 | 0.78 | PNMT (0.43) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL5343063 | 0.77 | PNMT (0.45) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL1610539 | 0.77 | PNMT (0.42) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL8676244 | 0.76 | PNMT (0.41) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL21449058 | 0.75 | NPC1 (0.43) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL6674618 | 0.75 | PNMT (0.43) | PNMTNPC1RAB9AHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210360-A4 | COMPOUNDS USEFUL TO MIMIC PEPTIDE BETA-STRANDS | UNIV CALIFORNIA (US) | 2005-03-02 | — | — | EP | disclosed |
| EP-1210360-A1 | COMPOUNDS USEFUL TO MIMIC PEPTIDE BETA-STRANDS | The Regents of the University of California (US) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001014412-A1 | COMPOUNDS USEFUL TO MIMIC PEPTIDE BETA-STRANDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-03-01 | — | — | WO | disclosed |