Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6129732 | 0.84 | PNMT (0.37) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL2316415 | 0.80 | RAB9A (0.42) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL6676496 | 0.80 | PNMT (0.44) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL4556624 | 0.79 | PNMT (0.43) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL28565431 | 0.79 | PNMT (0.43) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL5343063 | 0.78 | PNMT (0.45) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL1610539 | 0.78 | PNMT (0.42) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL8676244 | 0.76 | PNMT (0.41) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL21449058 | 0.76 | NPC1 (0.43) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL6674618 | 0.76 | PNMT (0.43) | PNMTNPC1RAB9AHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667704-A1 | MULTIPLE-ARM PEPTIDE COMPOUNDS, METHODS OF MANUFACTURE AND USE IN THERAPY | Imran, Mir A. (US) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005027957-A1 | MULTIPLE-ARM PEPTIDE COMPOUNDS, METHODS OF MANUFACTURE AND USE IN THERAPY | IMRAN MIR A (US) | 2005-03-31 | — | — | WO | disclosed |
| EP-1210360-A4 | COMPOUNDS USEFUL TO MIMIC PEPTIDE BETA-STRANDS | UNIV CALIFORNIA (US) | 2005-03-02 | — | — | EP | disclosed |
| EP-1210360-A1 | COMPOUNDS USEFUL TO MIMIC PEPTIDE BETA-STRANDS | The Regents of the University of California (US) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001014412-A1 | COMPOUNDS USEFUL TO MIMIC PEPTIDE BETA-STRANDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-03-01 | — | — | WO | disclosed |