SCHEMBL61299

SCHEMBL61299

COc1ccnc(Cl)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethoxycarbonyl Group SCHEMBL28048125 0.81 MTNR1A (0.35)
SCHEMBL5123913 0.80 HTT (0.38)
SCHEMBL19510786 0.80 ALDH1A1 (0.48)
SCHEMBL2221308 0.77 KDM4E (0.40)
SCHEMBL2017242 0.77 TSHR (0.39)
SCHEMBL30756042 0.76
SCHEMBL12015 0.76 CCR1 (0.41)
SCHEMBL29520064 0.76 CCR1 (0.41)
SCHEMBL2632782 0.76
SCHEMBL3930494 0.76 FGFR1 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1045 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2702044-B1 PROCESS FOR RILPIVIRINE HETERO RESEARCH FOUNDATION (IN) 2017-03-22 EP claimed
CN-103443074-B Heterocyclic amine derivative HOFFMAN-LA ROCHE LTD. (CH) 2016-04-13 CN claimed
CN-104320972-A Herbicidal composition comprising uracil compound as active ingredient DONGBU FARM HANNONG CO LTD 2015-01-28 CN claimed
US-20140228385-A1 PROCESS FOR RILPIVIRINE HETERO RESEARCH FOUNDATION (IN) 2014-08-14 US claimed
EP-2702044-A2 PROCESS FOR RILPIVIRINE Hetero Research Foundation (IN) 2014-03-05 EP claimed
WO-2012147091-A2 PROCESS FOR RILPIVIRINE HETERO RESEARCH FOUNDATION (IN) 2012-11-01 WO claimed
JP-61063665-A None JP disclosed
US-12629371-B2 Compositions and methods for inhibiting kinases INHIBIKASE THERAPEUTICS, INC. (US) 2026-05-19 US disclosed
WO-2026101724-A1 AMINO PYRIMIDINE AND AMINO TRIAZINE ANALOGS FOR TREATING CANCER NEREID THERAPEUTICS INCORPORATED (US) 2026-05-15 WO disclosed
WO-2026041663-A1 P2X7 RECEPTOR ANTAGONISTS BREYE THERAPEUTICS APS (DK) 2026-02-26 WO disclosed
US-12545662-B2 MK2 inhibitors and uses thereof XINTHERA, INC. (US) 2026-02-10 US disclosed
US-12545682-B2 Heterocyclic derivatives as P2X7 receptor antagonists BREYE THERAPEUTICS APS (DK) 2026-02-10 US disclosed
US-20260001846-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS SERVIER LAB (FR) 2026-01-01 US disclosed
WO-1994012494-A1 USE OF DIMETHYLBENZOFURANS AND DIMETHYLBENZOPYRANS AS 5-HT3 ANTAGONISTS JANSSEN PHARMACEUTICA N.V. (BE) 1994-06-09 WO disclosed
US-5266570-A Neuropsychiatric disorders IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-11-30 US disclosed
EP-0532178-A1 Methanoanthracenes as dopamine antagonists ZENECA LIMITED (GB) 1993-03-17 EP disclosed
EP-0246984-A2 Sulfonyl urea herbicides, their preparation, compositions containing them and their use RHONE-POULENC AGROCHIMIE (FR) 1987-11-25 EP disclosed
JP-S6163665-A 2-((3-PHENOXY)PROPYLAMINO)-4(1H)-PYRIMIDINONE DERIVATIVE HOKURIKU SEIYAKU CO LTD 1986-04-01 JP disclosed
US-4256738-A BACTERICIDES, PYRIMIDINYL, QUINAZOLINYL BOEHRINGER INGELHEIM GMBH (DE) 1981-03-17 US disclosed
EP-0001981-A1 9-(Omega-heteroarylamino-alkylamino)-erythromycins, their salts, processes for their preparation and medicaments containing them Dr. Karl Thomae GmbH (DE) 1979-05-30 EP disclosed