Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1692410 | 0.83 | MEN1 (0.37) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| SCHEMBL6469433 | 0.82 | TDP1 (0.33) | — | |
| SCHEMBL14739090 | 0.80 | MEN1 (0.35) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| SCHEMBL30815987 | 0.80 | CHRM1 (0.41) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| SCHEMBL192296 | 0.80 | MEN1 (0.39) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| SCHEMBL8160112 | 0.79 | SMPD1 (0.45) | MEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL8468329 | 0.79 | MEN1 (0.30) | MEN1KMT2ACYP1A2HRH1 | |
| SCHEMBL14739986 | 0.79 | GABBR2 (0.36) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| SCHEMBL5255308 | 0.79 | MEN1 (0.34) | MEN1KMT2ACYP2C19RECQLCYP1A2 | |
| SCHEMBL10931802 | 0.79 | AKT1 (0.44) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305322-A4 | DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF | DPHARM LTD (IL) | 2005-04-13 | — | — | EP | disclosed |
| EP-1305322-A2 | DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF | D-Pharm Ltd. (IL) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002011666-A2 | DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF | D-PHARM LTD. (IL) | 2002-02-14 | — | — | WO | disclosed |