Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.41 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL80350 | 0.86 | THRB (0.36) | SMN1; SMN2MEN1KMT2ACYP1A2HRH1 | |
| SCHEMBL1260408 | 0.83 | TSHR (0.37) | SMN1; SMN2MEN1KMT2ACYP1A2HRH1 | |
| Methacrylic Acid SCHEMBL5479590 | 0.83 | LMNA (0.35) | SMN1; SMN2MEN1KMT2ACYP1A2HRH1 | |
| SCHEMBL6130068 | 0.80 | MEN1 (0.33) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL17964294 | 0.80 | TSHR (0.46) | MEN1KMT2ALMNATSHRMAPT | |
| SCHEMBL1692410 | 0.79 | MEN1 (0.37) | MEN1KMT2ACYP1A2HRH1LMNA | |
| SCHEMBL14739090 | 0.79 | MEN1 (0.35) | SMN1; SMN2MEN1KMT2ACYP1A2HRH1 | |
| SCHEMBL14989008 | 0.79 | THRB (0.42) | SMN1; SMN2MEN1KMT2ACYP1A2HRH1 | |
| SCHEMBL31216396 | 0.78 | TSHR (0.40) | SMN1; SMN2MEN1KMT2ACYP1A2HRH1 | |
| SCHEMBL3630184 | 0.78 | SLC25A20 (0.38) | MEN1KMT2ACYP1A2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260060936-A1 | INDOLIUM-BASED STABILIZERS OF HYDROPHOBIC DRUGS | TECHNION RES & DEV FOUNDATION (IL) | 2026-03-05 | — | — | US | claimed |
| WO-2024047639-A1 | INDOLIUM-BASED STABILIZERS OF HYDROPHOBIC DRUGS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2024-03-07 | — | — | WO | claimed |
| US-20260060936-A1 | INDOLIUM-BASED STABILIZERS OF HYDROPHOBIC DRUGS | TECHNION RES & DEV FOUNDATION (IL) | 2026-03-05 | — | — | US | disclosed |
| WO-2024047639-A1 | INDOLIUM-BASED STABILIZERS OF HYDROPHOBIC DRUGS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2024-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260060936-A1 | INDOLIUM-BASED STABILIZERS OF HYDROPHOBIC DRUGS | CHRM1, CHRNA6, OPRM1 | CHRM1 1/4885SMN1; SMN2 565/4885CHRM5 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.