Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6006319 | 0.85 | SLC6A4 (0.64) | SLC6A4HTR2ATAAR1ALDH1A1CYP1A2 | |
| SCHEMBL12506240 | 0.82 | SLC6A4 (0.65) | SLC6A4HTR2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5010133 | 0.81 | SLC6A4 (0.58) | SLC6A4ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL613299 | 0.79 | CYP1A2 (0.47) | SLC6A4ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16721029 | 0.78 | SLC6A4 (0.64) | SLC6A4ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5010699 | 0.78 | SLC6A4 (0.64) | SLC6A4ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11081859 | 0.78 | SLC6A4 (0.69) | SLC6A4ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3676939 | 0.78 | SLC6A4 (0.59) | SLC6A4TAAR1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL4900483 | 0.78 | SLC6A4 (0.59) | SLC6A4TAAR1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL3680320 | 0.78 | SLC6A4 (0.59) | SLC6A4TAAR1ALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2299275-B1 | Classification of the oncofetal fibronection level for pregnancy-related indications | ADEZA BIOMEDICAL CORP (US) | 2018-03-07 | — | — | EP | disclosed |
| US-9513298-B2 | Methods for detecting oncofetal fibronectin | BANK OF AMERICA, N.A., AS COLLATERAL AGENT | 2016-12-06 | — | — | US | disclosed |
| US-20150044708-A1 | Methods for Detecting Oncofetal Fibronectin | HOLOGIC, INC. | 2015-02-12 | — | — | US | disclosed |
| US-8852872-B2 | Methods for detecting oncofetal fibronectin | HOLOGIC, INC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-20130171672-A1 | Methods for Detecting Oncofetal Fibronectin | HOLOGIC, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-8372581-B2 | Methods for detecting oncofetal fibronectin | CYTYC CORPORATION (US) | 2013-02-12 | — | — | US | disclosed |
| US-20120040356-A1 | Methods for Detecting Oncofetal Fibronectin | CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP | 2012-02-16 | — | — | US | disclosed |
| EP-1778874-B1 | ONCOFETAL FIBRONECTIN AS A MARKER FOR CERVICAL CANCER | ADEZA BIOMEDICAL CORP (US) | 2011-11-23 | — | — | EP | disclosed |
| EP-2299275-A2 | Classification of the oncofetal fibronection level for the indication of diseases and other conditions | ADEZA BIOMEDICAL CORPORATION (US) | 2011-03-23 | — | — | EP | disclosed |
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| EP-1778874-A2 | ONCOFETAL FIBRONECTIN AS A MARKER FOR DISEASE AND OTHER CONDITIONS AND METHODS FOR DETECTION OF ONCOFETAL FIBRONECTIN | ADEZA BIOMEDICAL CORPORATION (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006026020-A9 | ONCOFETAL FIBRONECTIN AS A MARKER FOR DISEASE AND OTHER CONDITIONS AND METHODS FOR DETECTION OF ONCOFETAL FIBRONECTIN | ADEZA BIOMEDICAL CORP (US) | 2006-07-06 | — | — | WO | disclosed |
| WO-2006026020-A2 | ONCOFETAL FIBRONECTIN AS A MARKER FOR DISEASE AND OTHER CONDITIONS AND METHODS FOR DETECTION OF ONCOFETAL FIBRONECTIN | ADEZA BIOMEDICAL CORPORATION (US) | 2006-03-09 | — | — | WO | disclosed |
| US-20060024724-A1 | Oncofetal fibronectin as a marker for health and disease | CYTYC SURGICAL PRODUCTS II LIMITED PARTNERSHIP | 2006-02-02 | — | — | US | disclosed |
| US-20060024725-A1 | Oncofetal fibronectin as a marker for pregnancy-related indications | THIRD WAVE TECHNOLOGIES, INC. | 2006-02-02 | — | — | US | disclosed |
| US-20060024757-A1 | Detection of oncofetal fibronectin for selection of concepti | CYTYC SURGICAL PRODUCTS II LIMITED PARTNERSHIP | 2006-02-02 | — | — | US | disclosed |
| US-20060024722-A1 | Samples for detection of oncofetal fibronectin and uses thereof | BIOLUCENT, LLC | 2006-02-02 | — | — | US | disclosed |
| US-20060024723-A1 | Methods for detecting oncofetal fibronectin | CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP | 2006-02-02 | — | — | US | disclosed |