Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ACP3 | P15309 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246866 | 0.90 | ALDH1A1 (0.54) | SLC6A4ALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL5010699 | 0.85 | SLC6A4 (0.64) | SLC6A4ALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL12506240 | 0.82 | SLC6A4 (0.65) | SLC6A4ALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL613009 | 0.81 | SLC6A4 (0.58) | SLC6A4ALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL5011023 | 0.78 | SLC6A4 (0.51) | SLC6A4ALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL16721029 | 0.78 | SLC6A4 (0.64) | SLC6A4ALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL6006319 | 0.78 | SLC6A4 (0.64) | SLC6A4ALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL11081859 | 0.78 | SLC6A4 (0.69) | SLC6A4ALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL5010807 | 0.78 | ALDH1A1 (0.54) | SLC6A4ALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL9852877 | 0.77 | SLC6A4 (0.54) | SLC6A4ALDH1A1CYP2C9CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053715-A | A kind of copper catalysis series connection cyclization constructs N- thiazoline indoles | 山东博苑医药化学有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-108947997-A | The copper catalysis series connection cyclization that a kind of oxygen participates in constructs N-5- carbonyl thiazole indoles | 山东博苑医药化学有限公司 | 2018-12-07 | — | — | CN | disclosed |
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |
| EP-0061910-B1 | NOVEL SUBSTITUTED IMIDAZOLES AND TRIAZOLES, FUNGICIDAL COMPOSITIONS CONTAINING THEM, THE USE THEREOF FOR COMBATING FUNGI AND PROCESSES FOR THE PREPARATION OF INTERMEDIATES FOR MAKING THE IMIDAZOLES AND TRIAZOLES | ROHM AND HAAS COMPANY (US) | 1986-08-27 | — | — | EP | disclosed |
| EP-0061910-A2 | Novel substituted imidazoles and triazoles, fungicidal compositions containing them, the use thereof for combating fungi and processes for the preparation of intermediates for making the imidazoles and triazoles | ROHM AND HAAS COMPANY (US) | 1982-10-06 | — | — | EP | disclosed |