SCHEMBL613299

SCHEMBL613299

NCC(c1c(Cl)cccc1Cl)c1cccc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.47
CYP2A6 P11509 1/20 0.47
ALDH1A1 P00352 2/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
SLC6A4 P31645 1/20 0.42
NISCH Q9Y2I1 1/20 0.40
ACP3 P15309 2/20 0.38
AOC3 Q16853 1/20 0.38
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL613009 0.79 SLC6A4 (0.58) CYP1A2ALDH1A1CYP2C9CYP2C19SLC6A4
SCHEMBL6999607 0.71 ALDH1A1 (0.41) CYP1A2ALDH1A1CYP2C9CYP2C19SLC6A4
SCHEMBL7000006 0.71 ALDH1A1 (0.41) CYP1A2ALDH1A1CYP2C9CYP2C19SLC6A4
SCHEMBL9751547 0.71 ALDH1A1 (0.52) CYP1A2ALDH1A1CYP2C9CYP2C19SLC6A4
SCHEMBL30509738 0.71 ALDH1A1 (0.52) CYP1A2ALDH1A1CYP2C9CYP2C19SLC6A4
SCHEMBL28707980 0.71 ALDH1A1 (0.52) CYP1A2ALDH1A1CYP2C9CYP2C19SLC6A4
SCHEMBL342584 0.71 ALDH1A1 (0.52) CYP1A2ALDH1A1CYP2C9CYP2C19SLC6A4
SCHEMBL29435914 0.71 ALDH1A1 (0.52) CYP1A2ALDH1A1CYP2C9CYP2C19SLC6A4
SCHEMBL1527192 0.71 ALDH1A1 (0.52) CYP1A2ALDH1A1CYP2C9CYP2C19SLC6A4
Hydrochloric Acid SCHEMBL2455223 0.69 ALDH1A1 (0.50) CYP1A2ALDH1A1CYP2C9CYP2C19SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2299275-B1 Classification of the oncofetal fibronection level for pregnancy-related indications ADEZA BIOMEDICAL CORP (US) 2018-03-07 EP disclosed
US-9513298-B2 Methods for detecting oncofetal fibronectin BANK OF AMERICA, N.A., AS COLLATERAL AGENT 2016-12-06 US disclosed
US-20150044708-A1 Methods for Detecting Oncofetal Fibronectin HOLOGIC, INC. 2015-02-12 US disclosed
US-8852872-B2 Methods for detecting oncofetal fibronectin HOLOGIC, INC. (US) 2014-10-07 US disclosed
US-20130171672-A1 Methods for Detecting Oncofetal Fibronectin HOLOGIC, INC. (US) 2013-07-04 US disclosed
US-8372581-B2 Methods for detecting oncofetal fibronectin CYTYC CORPORATION (US) 2013-02-12 US disclosed
US-20120040356-A1 Methods for Detecting Oncofetal Fibronectin CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP 2012-02-16 US disclosed
EP-1778874-B1 ONCOFETAL FIBRONECTIN AS A MARKER FOR CERVICAL CANCER ADEZA BIOMEDICAL CORP (US) 2011-11-23 EP disclosed
US-7943294-B2 Methods for detecting oncofetal fibronectin HOLOGIC, INC. (US) 2011-05-17 US disclosed
EP-2299275-A2 Classification of the oncofetal fibronection level for the indication of diseases and other conditions ADEZA BIOMEDICAL CORPORATION (US) 2011-03-23 EP disclosed
EP-1778874-A2 ONCOFETAL FIBRONECTIN AS A MARKER FOR DISEASE AND OTHER CONDITIONS AND METHODS FOR DETECTION OF ONCOFETAL FIBRONECTIN ADEZA BIOMEDICAL CORPORATION (US) 2007-05-02 EP disclosed
WO-2006026020-A9 ONCOFETAL FIBRONECTIN AS A MARKER FOR DISEASE AND OTHER CONDITIONS AND METHODS FOR DETECTION OF ONCOFETAL FIBRONECTIN ADEZA BIOMEDICAL CORP (US) 2006-07-06 WO disclosed
WO-2006026020-A2 ONCOFETAL FIBRONECTIN AS A MARKER FOR DISEASE AND OTHER CONDITIONS AND METHODS FOR DETECTION OF ONCOFETAL FIBRONECTIN ADEZA BIOMEDICAL CORPORATION (US) 2006-03-09 WO disclosed
US-20060024724-A1 Oncofetal fibronectin as a marker for health and disease CYTYC SURGICAL PRODUCTS II LIMITED PARTNERSHIP 2006-02-02 US disclosed
US-20060024725-A1 Oncofetal fibronectin as a marker for pregnancy-related indications THIRD WAVE TECHNOLOGIES, INC. 2006-02-02 US disclosed
US-20060024757-A1 Detection of oncofetal fibronectin for selection of concepti CYTYC SURGICAL PRODUCTS II LIMITED PARTNERSHIP 2006-02-02 US disclosed
US-20060024723-A1 Methods for detecting oncofetal fibronectin CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP 2006-02-02 US disclosed
US-20060024722-A1 Samples for detection of oncofetal fibronectin and uses thereof BIOLUCENT, LLC 2006-02-02 US disclosed