Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | CDC25A | P30304 | 2/20 | 0.53 |
| ▸ | CDC25B | P30305 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19816482 | 0.98 | ALDH1A1 (0.59) | MAPTALDH1A1HDAC1HDAC3HDAC2 | |
| SCHEMBL859720 | 0.98 | ALDH1A1 (0.59) | MAPTALDH1A1HDAC1HDAC3HDAC2 | |
| SCHEMBL8390655 | 0.98 | ALDH1A1 (0.59) | MAPTALDH1A1HDAC1HDAC3HDAC2 | |
| SCHEMBL16691726 | 0.98 | ALDH1A1 (0.59) | MAPTALDH1A1HDAC1HDAC3HDAC2 | |
| SCHEMBL19816825 | 0.98 | ALDH1A1 (0.59) | MAPTALDH1A1HDAC1HDAC3HDAC2 | |
| SCHEMBL15068944 | 0.98 | ALDH1A1 (0.59) | MAPTALDH1A1HDAC1HDAC3HDAC2 | |
| SCHEMBL4624978 | 0.98 | ALDH1A1 (0.59) | MAPTALDH1A1HDAC1HDAC3HDAC2 | |
| Water SCHEMBL28193859 | 0.96 | HDAC1 (0.57) | MAPTALDH1A1HDAC1HDAC3HDAC2 | |
| SCHEMBL2177141 | 0.94 | ALDH1A1 (0.64) | MAPTALDH1A1HDAC1HDAC3HDAC2 | |
| SCHEMBL27609848 | 0.92 | ALDH1A1 (0.61) | MAPTALDH1A1HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108516941-A | A kind of 3-（Phenyl amino）The preparation method of ethyl propionate class compound | 济南大学 | 2018-09-11 | — | — | CN | claimed |
| EP-1416934-A4 | PROTEIN KINASE INHIBITORS COMPRISING ATP MIMETICS CONJUGATED TO PEPTIDES OR PEPTIDOMIMETICS | PEPTOR LTD (IL) | 2005-11-02 | — | — | EP | claimed |
| EP-1416934-A2 | PROTEIN KINASE INHIBITORS COMPRISING ATP MIMETICS CONJUGATED TO PEPTIDES OR PEPTIDOMIMETICS | Peptor Ltd. (IL) | 2004-05-12 | — | — | EP | claimed |
| WO-2003010281-A2 | PROTEIN KINASE INHIBITORS COMPRISING ATP MIMETICS CONJUGATED TO PEPTIDES OR PEPTIDOMIMETICS | PEPTOR LTD. (IL) | 2003-02-06 | — | — | WO | claimed |
| CN-117362188-A | Synthesis method of alpha-substituted deuterated amino acid ester | 广州医科大学 | 2024-01-09 | — | — | CN | disclosed |
| CN-110234631-A | For treating the composition of hypertension and/or fibrosis | 维克特斯生物系统有限公司 | 2019-09-13 | — | — | CN | disclosed |
| EP-3488000-A1 | METHODS AND MATERIALS FOR BIOSYNTHESIZING MULTIFUNCTIONAL, MULTIVARIATE MOLECULES VIA CARBON CHAIN MODIFICATION | INVISTA Textiles (U.K.) Limited (GB) | 2019-05-29 | — | — | EP | disclosed |
| CN-108516941-A | A kind of 3-（Phenyl amino）The preparation method of ethyl propionate class compound | 济南大学 | 2018-09-11 | — | — | CN | disclosed |
| WO-2018022633-A1 | METHODS AND MATERIALS FOR BIOSYNTHESIZING MULTIFUNCTIONAL, MULTIVARIATE MOLECULES VIA CARBON CHAIN MODIFICATION | INVISTA TEXTILES (U.K.) LIMITED (GB) | 2018-02-01 | — | — | WO | disclosed |
| EP-3126006-A1 | ANTI-EGFR ANTIBODIES AND ANTIBODY DRUG CONJUGATES | AbbVie Inc. (US) | 2017-02-08 | — | — | EP | disclosed |
| CN-103524559-B | Ester derivant of polysubstituted 4-methylamino benzenecarboximidamide and its production and use | 西藏海思科药业集团股份有限公司 | 2016-09-28 | — | — | CN | disclosed |
| CN-105439945-A | Aryloxy anilino propionic ester compound and application thereof as herbicide | UNIV YANGTZE | 2016-03-30 | — | — | CN | disclosed |
| WO-2015143382-A1 | ANTI-EGFR ANTIBODIES AND ANTIBODY DRUG CONJUGATES | ABBVIE INC. (US) | 2015-09-24 | — | — | WO | disclosed |
| CN-103524559-A | Ester derivatives of multi-substituted 4-methylamino-benzamidine as well as preparation method and application of ester derivatives | TIBET HAISCO PHARMACEUTICAL GROUP CO LTD | 2014-01-22 | — | — | CN | disclosed |
| WO-2008007391-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF VALSARTAN | SATYANARAYANA REDDY MANNE (IN) | 2008-01-17 | — | — | WO | disclosed |