SCHEMBL6130600

SCHEMBL6130600

CC(O)(O)[CH]c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.41
EGFR P00533 1/20 0.39
ALDH1A1 P00352 5/20 0.38
TSHR P16473 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
AKR1C3 P42330 1/20 0.38
GLA P06280 1/20 0.38
MAOB P27338 1/20 0.38
CYP2A6 P11509 1/20 0.38
NPC1 O15118 1/20 0.36
LMNA P02545 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALOX15 P16050 2/20 0.36
HDAC3 O15379 1/20 0.36
TNKS O95271 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17629414 0.84 CYP2C19 (0.41) CYP2C19EGFRALDH1A1TSHRTDP1
SCHEMBL512987 0.78 ALDH1A1 (0.41) CYP2C19EGFRALDH1A1TSHRTDP1
SCHEMBL8474272 0.77 MEN1 (0.36) CYP2C19EGFRALDH1A1TSHRTDP1
SCHEMBL7903413 0.75 CYP2C19 (0.57) CYP2C19EGFRALDH1A1TSHRTDP1
SCHEMBL27517084 0.74 ALDH1A1 (0.38) CYP2C19ALDH1A1TSHRTDP1AKR1C3
SCHEMBL17331000 0.74 ALDH1A1 (0.38) CYP2C19EGFRALDH1A1TSHRTDP1
SCHEMBL27953917 0.74 ALDH1A1 (0.38) CYP2C19EGFRALDH1A1TSHRTDP1
SCHEMBL3032334 0.74 ALDH1A1 (0.43) CYP2C19EGFRALDH1A1TSHRTDP1
SCHEMBL14754788 0.73 MAPT (0.48) CYP2C19EGFRALDH1A1TSHRTDP1
SCHEMBL28021109 0.73 EGFR (0.37) CYP2C19EGFRALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4929644-A QUATERNARY AMMONIUM COMPOUNDS, SMECTITE CLAYS RHEOX, INC. (US) 1990-05-29 US claimed
EP-0265101-A2 Biocidal thickening additive for an organic composition RHEOX INTERNATIONAL, INC. (US) 1988-04-27 EP claimed
EP-1448688-B1 THERMOSETTING INORGANIC CLAY NANODISPERSIONS AND THEIR USE ASHLAND LICENSING & IP LLC (US) 2017-03-08 EP disclosed
EP-1448688-A4 THERMOSETTING INORGANIC CLAY NANODISPERSIONS AND THEIR USE ASHLAND INC (US) 2005-11-02 EP disclosed
US-6887931-B2 Thermosetting inorganic clay nanodispersions and their use ASHLAND INC. (US) 2005-05-03 US disclosed
EP-1448688-A2 THERMOSETTING INORGANIC CLAY NANODISPERSIONS AND THEIR USE ASHLAND INC. (US) 2004-08-25 EP disclosed
WO-2003051282-A2 THERMOSETTING INORGANIC CLAY NANODISPERSIONS AND THEIR USE ASHLAND INC. (US) 2003-06-26 WO disclosed
US-20030105208-A1 Thermosetting inorganic clay nanodispersions and their use ASHLAND INC. 2003-06-05 US disclosed
US-20030100657-A1 Thermosetting inorganic clay nanodispersions and their use INEOS COMPOSITES IP, LLC 2003-05-29 US disclosed
US-4929644-A QUATERNARY AMMONIUM COMPOUNDS, SMECTITE CLAYS RHEOX, INC. (US) 1990-05-29 US disclosed
EP-0265101-A2 Biocidal thickening additive for an organic composition RHEOX INTERNATIONAL, INC. (US) 1988-04-27 EP disclosed