Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28021109 | 0.83 | EGFR (0.37) | MEN1KMT2ACYP2C19TTRALOX5 | |
| SCHEMBL16552541 | 0.79 | CYP2C19 (0.50) | MEN1KMT2ACYP2C19TTRALOX5 | |
| SCHEMBL28111008 | 0.78 | CYP1B1 (0.36) | MEN1KMT2ACYP2C19EGFRTSHR | |
| SCHEMBL17629414 | 0.77 | CYP2C19 (0.41) | CYP2C19EGFRTSHRALDH1A1TDP1 | |
| SCHEMBL6130600 | 0.77 | CYP2C19 (0.41) | CYP2C19EGFRTSHRALDH1A1TDP1 | |
| SCHEMBL3073246 | 0.71 | MEN1 (0.41) | MEN1KMT2ATSHRALDH1A1TDP1 | |
| SCHEMBL2362850 | 0.71 | ALDH1A1 (0.39) | MEN1KMT2ACYP2C19TSHRALDH1A1 | |
| SCHEMBL512987 | 0.71 | ALDH1A1 (0.41) | CYP2C19EGFRTSHRALDH1A1TDP1 | |
| SCHEMBL6599306 | 0.70 | KDM4E (0.42) | CYP2C19KDM4ETSHRALDH1A1CYP3A4 | |
| SCHEMBL10519823 | 0.68 | RELA (0.36) | MEN1KMT2ACYP2C19EGFRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004954-A | TREATING GRAFT-VERSUS-HOST DISEASE AND AUTOIMMUNE DISEASES; ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-12-21 | — | — | US | disclosed |