Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | SAT1 | P21673 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29002323 | 0.90 | MEN1 (0.50) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL15264130 | 0.88 | MEN1 (0.52) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL18364665 | 0.88 | MEN1 (0.52) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL17029461 | 0.88 | MEN1 (0.52) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL11344130 | 0.87 | MEN1 (0.64) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL11344512 | 0.87 | MEN1 (0.64) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL13538736 | 0.87 | MEN1 (0.64) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL11347984 | 0.87 | MEN1 (0.64) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL8219819 | 0.87 | MEN1 (0.64) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL11350056 | 0.87 | MEN1 (0.64) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050064468-A1 | concentration, removing or separation of nucleotide bases or nucleotide sequences containing bases from solid supports | IBC ADVANCED TECHNOLOGIES, INC. | 2005-03-24 | — | — | US | disclosed |
| EP-1453602-A4 | COMPOSITIONS AND METHODS FOR SEPARATING HETEROCYCLIC AROMATIC AMINE BASES, NUCLEOSIDES, NUCLEOTIDES, AND NUCLEOTIDE SEQUENCES | IBC ADVANCED TECH INC (US) | 2005-01-12 | — | — | EP | disclosed |
| EP-1453602-A2 | COMPOSITIONS AND METHODS FOR SEPARATING HETEROCYCLIC AROMATIC AMINE BASES, NUCLEOSIDES, NUCLEOTIDES, AND NUCLEOTIDE SEQUENCES | IBC ADVANCED TECHNOLOGIES, INC. (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6774082-B2 | COMPOSITION FOR USE IN THE SEPARATION OF PREFERENTIAL BIOPOLYMERS FROM SAMPLE | IBC ADVANCED TECHNOLOGIES, INC. | 2004-08-10 | — | — | US | disclosed |
| US-20030050458-A1 | Compositions and methods for separating heterocyclic aromatic amine bases, nucleosides, nucleotides, and nucleotide sequences | IBC ADVANCED TECHNOLOGIES, INC. | 2003-03-13 | — | — | US | disclosed |
| WO-2002092766-A2 | COMPOSITIONS AND METHODS FOR SEPARATING HETEROCYCLIC AROMATIC AMINE BASES, NUCLEOSIDES, NUCLEOTIDES, AND NUCLEOTIDE SEQUENCES | IBC ADVANCED TECHNOLOGIES, INC. (US) | 2002-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030050458-A1 | Compositions and methods for separating heterocyclic aromatic amine bases, nucleosides, nucleotides, and nucleotide sequences | NUDT1, ATIC, PNP | MEN1 3288/4885KMT2A 967/4885THRB 4461/4885 |
| US-20050064468-A1 | concentration, removing or separation of nucleotide bases or nucleotide sequences containing bases from solid supports | NUDT1, PCNA, NSUN2 | MEN1 2474/4885KMT2A 571/4885THRB 4588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.