Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2940083 | 0.96 | KCNB1 (0.33) | ALDH1A1PPARGPPARAKCNA5KCNH2 | |
| SCHEMBL2353039 | 0.85 | GLS (0.36) | ALDH1A1MEN1KMT2A | |
| SCHEMBL2936801 | 0.85 | S1PR1 (0.35) | KCNA5KCNH2KCNB1 | |
| SCHEMBL2939235 | 0.81 | PRTN3 (0.46) | ALDH1A1LMNA | |
| SCHEMBL2350401 | 0.81 | GLS (0.37) | MEN1KMT2A | |
| SCHEMBL6130843 | 0.78 | S1PR1 (0.37) | TLR7LMNA | |
| SCHEMBL2940407 | 0.75 | PPARG (0.35) | PPARGPPARA | |
| SCHEMBL2933823 | 0.74 | PRTN3 (0.44) | PPARG | |
| SCHEMBL2355879 | 0.71 | PRTN3 (0.47) | MEN1KMT2APPARG | |
| SCHEMBL2354971 | 0.69 | GLS (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497300-A2 | PLASMA CARBOXYPEPTIDASE B INHIBITORS | Schering Aktiengesellschaft (DE) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003080631-A2 | PLASMA CARBOXYPEPTIDASE B INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |