SCHEMBL6131050

SCHEMBL6131050

O=C(O)[C@]1(S)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O.[Au]

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PYGB P11216 8/20 0.43
PYGL P06737 3/20 0.43
PYGM P11217 2/20 0.43
LMNA P02545 1/20 0.35
GBA1 P04062 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27936287 0.98 PYGB (0.44) PYGBPYGLPYGMLMNAGBA1
SCHEMBL3232264 0.82 PYGB (0.50) PYGBPYGLPYGMLMNAGBA1
SCHEMBL7454320 0.82 PYGB (0.43) PYGBPYGLPYGM
SCHEMBL17422130 0.78 HK1 (0.41) PYGBPYGLPYGM
SCHEMBL1842510 0.76 PYGB (0.45) PYGBPYGLPYGMLMNAGBA1
SCHEMBL28664605 0.76 PYGB (0.45) PYGBPYGLPYGMLMNAGBA1
SCHEMBL1842511 0.76 PYGB (0.45) PYGBPYGLPYGMLMNAGBA1
SCHEMBL9862851 0.76 PYGB (0.45) PYGBPYGLPYGMLMNAGBA1
SCHEMBL1521577 0.74 PYGB (0.40) PYGBPYGLPYGM
SCHEMBL23358401 0.73 PYGB (0.44) PYGBPYGLPYGM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6908761-B1 Transcriptional activators OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-06-21 US disclosed
US-20050019710-A1 Silver halide emulsion and image-forming method using silver halide color photographic light-sensitive material containing the same FUJI PHOTO FILM CO., LTD. 2005-01-27 US disclosed
US-6780579-B2 Silver halide emulsion and image-forming method using silver halide color photographic light-sensitive material containing the same FUJI PHOTO FILM CO., LTD. (JP) 2004-08-24 US disclosed
US-20040002026-A1 Silver halide emulsion and image-forming method using silver halide color photographic light-sensitive material containing the same FUJI PHOTO FILM CO., LTD. 2004-01-01 US disclosed
US-4680286-A Use of selenium-containing compounds for negating the toxic effects of gold compounds used in the treatment of rheumatoid arthritis, and a novel selenium-containing gold compound and use thereof as an anti-rheumatoid arthritis medicine STOCKEL RICHARD F (US) 1987-07-14 US disclosed
EP-0153307-A4 USE OF SELENIUM-CONTAINING COMPOUNDS FOR NEGATING THE TOXIC EFFECTS OF GOLD COMPOUNDS USED IN THE TREATMENT OF RHEUMATOID ARTHRITIS, AND A NOVEL SELENIUM-CONTAINING GOLD COMPOUND AND USE THEREOF AS AN ANTI-RHEUMATOID ARTHRITIS MEDICINE. STOCKEL RICHARD F (US) 1987-03-12 EP disclosed
EP-0153307-A1 USE OF SELENIUM-CONTAINING COMPOUNDS FOR NEGATING THE TOXIC EFFECTS OF GOLD COMPOUNDS USED IN THE TREATMENT OF RHEUMATOID ARTHRITIS, AND A NOVEL SELENIUM-CONTAINING GOLD COMPOUND AND USE THEREOF AS AN ANTI-RHEUMATOID ARTHRITIS MEDICINE STOCKEL, Richard F. (US) 1985-09-04 EP disclosed
WO-1985000747-A1 USE OF SELENIUM-CONTAINING COMPOUNDS FOR NEGATING THE TOXIC EFFECTS OF GOLD COMPOUNDS USED IN THE TREATMENT OF RHEUMATOID ARTHRITIS, AND A NOVEL SELENIUM-CONTAINING GOLD COMPOUND AND USE THEREOF AS AN ANTI-RHEUMATOID ARTHRITIS MEDICINE STOCKEL RICHARD F 1985-02-28 WO disclosed