Known targets — ChEMBL curated mechanism
ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1HRH1HTR7IDH1IDH2IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HMGCR | P04035 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 4/20 | 0.38 |
| ▸ | SLC13A5 | Q86YT5 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL27759607 | 1.00 | ALDH1A1 (0.75) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| Citric Acid SCHEMBL571532 | 1.00 | ALDH1A1 (0.75) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| Citric Acid SCHEMBL756899 | 1.00 | ALDH1A1 (0.75) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| Citric Acid SCHEMBL4646062 | 0.98 | ALDH1A1 (0.71) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| Citric Acid SCHEMBL9538164 | 0.98 | ALDH1A1 (0.71) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| Citric Acid SCHEMBL23012734 | 0.98 | ALDH1A1 (0.71) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| Citric Acid SCHEMBL7742094 | 0.98 | ALDH1A1 (0.71) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| Citric Acid SCHEMBL9538158 | 0.98 | ALDH1A1 (0.71) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| Citric Acid SCHEMBL7742087 | 0.98 | ALDH1A1 (0.71) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| Citric Acid SCHEMBL8056530 | 0.98 | ALDH1A1 (0.71) | ALDH1A1TSHRLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117281889-A | Oxygen spray for wound repair and debridement, and preparation method and application thereof | 清华大学深圳国际研究生院 | 2023-12-26 | — | — | CN | claimed |
| CN-117122038-A | Steam explosion peeling method for green peppers | 海口植之素生物资源研究所有限公司 | 2023-11-28 | — | — | CN | claimed |
| CN-109679864-B | Strain for producing transglycosylation active beta-galactosidase and method for producing galactooligosaccharide by using same | 石河子大学 | 2023-11-10 | — | — | CN | claimed |
| CN-116874803-A | Antibacterial dendritic polyester polymer and preparation method and application thereof | 清华大学深圳国际研究生院 | 2023-10-13 | — | — | CN | claimed |
| CN-116410514-A | Degradable gelatin sponge with memory function and preparation method thereof | 西安交通大学 | 2023-07-11 | — | — | CN | claimed |
| CN-116410486-A | Amino modified gelatin-based cross-linked material and preparation method thereof, amino-gelatin sponge and preparation method thereof | 西安交通大学 | 2023-07-11 | — | — | CN | claimed |
| CN-110184317-B | Preparation method and application of glycosylated trilobatin and derivative | 广东金骏康生物技术有限公司 | 2023-05-26 | — | — | CN | claimed |
| CN-110967488-B | Test strip, kit and method for measuring glycosylated hemoglobin | 深圳优迪生物技术有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-115703889-A | Hydrogel with postoperative hemostasis and anti-adhesion functions and preparation method thereof | 西安交通大学 | 2023-02-17 | — | — | CN | claimed |
| CN-112931786-B | Preparation method of pea yogurt with low beany flavor | 江南大学 | 2023-01-06 | — | — | CN | claimed |
| CN-110967488-A | Test strip, kit and method for measuring glycosylated hemoglobin | 深圳优迪生物技术有限公司 | 2020-04-07 | — | — | CN | claimed |
| CN-110205351-A | A kind of preparation method and applications glycosylating naringenin | 广东金骏康生物技术有限公司 | 2019-09-06 | — | — | CN | claimed |
| CN-110156855-A | Glycosylated flavanoid and its preparation method and application | 广东金骏康生物技术有限公司 | 2019-08-23 | — | — | CN | claimed |
| CN-110156852-A | A kind of preparation method and applications glycosylating new hesperidin methyl dihydrochalcone | 广东金骏康生物技术有限公司 | 2019-08-23 | — | — | CN | claimed |
| CN-110105409-A | A kind of preparation method and applications glycosylating hesperetin | 广东金骏康生物技术有限公司 | 2019-08-09 | — | — | CN | claimed |
| CN-109679864-A | A method of it producing the bacterial strain for turning glycosyl active p-galactosidase and produces galactooligosaccharide with the enzyme | 石河子大学 | 2019-04-26 | — | — | CN | claimed |
| CN-108042507-A | A kind of more twenty alcohol microballoons and preparation method and application | 北京颐方生物科技有限公司 | 2018-05-18 | — | — | CN | claimed |
| US-20050020081-A1 | Etchant composition for molybdenum and method of using same | LG DISPLAY CO., LTD. (KR) | 2005-01-27 | — | — | US | claimed |
| US-6797621-B2 | Etchant composition for molybdenum and method of using same | LG.PHILIPS LCD CO., LTD. (KR) | 2004-09-28 | — | — | US | claimed |
| US-20010034139-A1 | Etchant composition for molybdenum and method of using same | LG DISPLAY CO., LTD. (KR) | 2001-10-25 | — | — | US | claimed |