Itaconate

Itaconate

SCHEMBL6131145

C=C(CC(=O)O)C(=O)O.C=CC=CCC(=C)C(=O)OC

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.49
HSD17B10 Q99714 1/20 0.49
ALDH1A1 P00352 1/20 0.31
EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27000 0.88 ALDH1A1 (0.38) ALDH1A1
Acrylic Acid SCHEMBL17746702 0.85 ALOX15 (0.40) ALOX15HSD17B10ALDH1A1
SCHEMBL347875 0.82 ALDH1A1 (0.52) ALDH1A1
Acrylonitrile SCHEMBL17360697 0.79 ALDH1A1 (0.31) ALDH1A1
Itaconate SCHEMBL10984219 0.79 ALOX15 (0.56) ALOX15HSD17B10ALDH1A1EGLN1
Itaconate SCHEMBL11290333 0.78 ALOX15 (0.45) ALOX15HSD17B10
SCHEMBL1394549 0.77 ALOX15 (0.41) ALOX15HSD17B10ALDH1A1
Acrylic Acid Ethyl Ester SCHEMBL17181015 0.77 TSHR (0.38) HSD17B10ALDH1A1
Styrene SCHEMBL2019985 0.77 ALDH1A1 (0.39) ALDH1A1
Serine SCHEMBL7648632 0.77 GRIK1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6514662-B2 For photographic art, in particular for scanners, image setters and so forth. FUJI PHOTO FILM CO., LTD. (JP) 2003-02-04 US claimed
EP-1584978-A1 Photothermographic material and image forming method FUJI PHOTO FILM CO., LTD. (JP) 2005-10-12 EP disclosed
US-6930698-B2 Image formation on heat-developable light-sensitive material and image forming apparatus FUJI PHOTO FILM CO., LTD. (JP) 2005-08-16 US disclosed
US-20050024469-A1 Image formation on heat-developable light-sensitive material and image forming apparatus FUJI PHOTO FILM CO., LTD. 2005-02-03 US disclosed
US-6814506-B2 Method of density correction in heat developing apparatus and heat developing apparatus capable of density correction FUJI PHOTO FILM CO., LTD. (JP) 2004-11-09 US disclosed
US-6791593-B2 Image formation on heat-developable light-sensitive material and image forming apparatus FUJI PHOTO FILM CO., LTD. (JP) 2004-09-14 US disclosed
US-20030219248-A1 Method of density correction in heat developing apparatus and heat developing apparatus capable of density correction FUJI PHOTO FILM CO., LTD. 2003-11-27 US disclosed
US-20030091347-A1 Image formation on heat-developable light-sensitive material and image forming apparatus FUJI PHOTO FILM CO., LTD. 2003-05-15 US disclosed
EP-1276006-A1 Image formation on heat-developable light-sensitive material and image forming apparatus FUJI PHOTO FILM CO., LTD. (JP) 2003-01-15 EP disclosed
US-20020146654-A1 Heat-developable image recording material FUJI PHOTO FILM CO., LTD. (JP) 2002-10-10 US disclosed