Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | FDPS | P14324 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28477273 | 0.98 | OPRM1 (0.42) | OPRM1SPHK1LMNADNM1ADH1B | |
| SCHEMBL11286280 | 0.80 | CA2 (0.44) | OPRM1SPHK1LMNACA2ACE2 | |
| SCHEMBL19577206 | 0.80 | OPRM1 (0.39) | OPRM1SPHK1LMNADNM1ADH1B | |
| SCHEMBL615029 | 0.78 | OPRM1 (0.46) | OPRM1SPHK1LMNADNM1ADH1B | |
| SCHEMBL6700324 | 0.78 | OPRM1 (0.46) | OPRM1SPHK1LMNADNM1ADH1B | |
| SCHEMBL23803921 | 0.78 | OPRM1 (0.46) | OPRM1SPHK1LMNADNM1ADH1B | |
| SCHEMBL8066854 | 0.78 | OPRM1 (0.46) | OPRM1SPHK1LMNADNM1ADH1B | |
| SCHEMBL6060338 | 0.78 | OPRM1 (0.46) | OPRM1SPHK1LMNADNM1ADH1B | |
| SCHEMBL10587140 | 0.78 | OPRM1 (0.46) | OPRM1SPHK1LMNADNM1ADH1B | |
| SCHEMBL6408263 | 0.78 | OPRM1 (0.46) | OPRM1SPHK1LMNADNM1ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403320-B1 | Polyester resin composition | FUJI PHOTO FILM CO LTD (JP) | 2005-12-14 | — | — | EP | disclosed |
| US-6861468-B2 | Polyester resin composition | FUJI PHOTO FILM CO., LTD. (JP) | 2005-03-01 | — | — | US | disclosed |
| US-20040092641-A1 | Polyester resin composition | FUJI PHOTO FILM CO., LTD. | 2004-05-13 | — | — | US | disclosed |
| EP-1403320-A1 | Polyester resin composition | FUJI PHOTO FILM CO., LTD. (JP) | 2004-03-31 | — | — | EP | disclosed |