Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603682 | 0.79 | HDAC4 (0.39) | ALDH1A1TSHRKMT2AMEN1THRB | |
| Trimethylammonium SCHEMBL28286453 | 0.78 | RET (0.38) | RET | |
| SCHEMBL3210560 | 0.76 | MAPT (0.33) | ALDH1A1TSHRRETP2RX4KMT2A | |
| SCHEMBL1028466 | 0.75 | HTR2A (0.39) | ALDH1A1RETKDM4E | |
| SCHEMBL8865153 | 0.75 | GID4 (0.46) | KMT2AKDM4EMEN1KDM1A | |
| Methane SCHEMBL28813011 | 0.74 | HTR2A (0.38) | ALDH1A1RETKDM4E | |
| SCHEMBL9145143 | 0.74 | HTR2A (0.38) | ALDH1A1RETKDM4E | |
| SCHEMBL9145856 | 0.74 | HTR2A (0.38) | ALDH1A1RETKDM4E | |
| Ammonia Solution, Strong SCHEMBL21245914 | 0.74 | HTR2A (0.38) | ALDH1A1RETKDM4E | |
| Lithium SCHEMBL9145147 | 0.74 | HTR2A (0.38) | ALDH1A1RETKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919412-B1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten with a donor bridge | BASELL POLYOLEFINE GMBH (DE) | 2005-07-19 | — | — | US | disclosed |
| US-6838563-B2 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | BASELL POLYOLEFINS (DE) | 2005-01-04 | — | — | US | disclosed |
| US-6787498-B2 | AS CATALYSTS FOR POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2004-09-07 | — | — | US | disclosed |
| US-6699948-B2 | AS CATALYSTS FOR POLYMERIZATION OF OLEFINS | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-02 | — | — | US | disclosed |
| EP-1288219-A2 | Monocyclopentadienyl complexes of chromium molybdenum or tungsten with a donor bridge | Basell Polyolefine GmbH (DE) | 2003-03-05 | — | — | EP | disclosed |
| US-20030036658-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | MIHAN SHAHRAM (DE) | 2003-02-20 | — | — | US | disclosed |
| EP-1212333-B1 | MONOCYCLOPENTADIENYL COMPLEXES OF CHROMIUM, MOLYBDENUM OR TUNGSTEN WITH A DONOR BRIDGE | BASELL POLYOLEFINE GMBH (DE) | 2003-02-12 | — | — | EP | disclosed |
| US-6437161-B1 | OLEFIN POLYMERIZATION CATALYSTS; SUBSTITUENT ON THE CYCLOPENTADIENYL RING CARRIES A DONOR FUNCTION WHICH IS BONDED RIGIDLY, NOT EXCLUSIVELY VIA SP3-HYBRIDIZED CARBON OR SILICON ATOMS, | BASF AKTIENGESELLSCHAFT (DE) | 2002-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030036658-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | SKIC3, ORC3, MCM3 | ALDH1A1 4462/4885TSHR 4384/4885RET 3244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.