SCHEMBL6449828

SCHEMBL6449828

C=CCC(O)C(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8548443 0.77 GRIK1 (0.61)
SCHEMBL246812 0.76
SCHEMBL5674658 0.76
SCHEMBL4079703 0.76
SCHEMBL6131545 0.76 GRIK1 (0.40)
SCHEMBL174976 0.76 GRIK1 (0.50)
SCHEMBL16994566 0.76
SCHEMBL18709935 0.76
SCHEMBL1045132 0.74
SCHEMBL2759244 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4363511-A1 ELECTRODEPOSITABLE COATING COMPOSITIONS PPG Industries Ohio Inc. (US) 2024-05-08 EP claimed
EP-3580290-B1 LOW-TEMPERATURE CURING COATING COMPOSITIONS PPG IND OHIO INC (US) 2024-05-01 EP claimed
US-11952514-B2 Low-temperature curing adhesive compositions PPG INDUSTRIES OHIO, INC. (US) 2024-04-09 US claimed
WO-2023279087-A1 ELECTRODEPOSITABLE COATING COMPOSITIONS PPG INDUSTRIES OHIO, INC. (US) 2023-01-05 WO claimed
EP-3580253-B1 LOW-TEMPERATURE CURING ADHESIVE COMPOSITIONS PPG IND OHIO INC (US) 2021-04-07 EP claimed
WO-2018148306-A1 LOW-TEMPERATURE CURING COATING COMPOSITIONS PPG INDUSTRIES OHIO, INC. (US) 2018-08-16 WO claimed
WO-2018148323-A1 LOW-TEMPERATURE CURING ADHESIVE COMPOSITIONS PPG INDUSTRIES OHIO, INC. (US) 2018-08-16 WO claimed
EP-1379522-B1 DIHYDRO-BENZO(b)(1,4)DIAZEPIN-2-ONE DERIVATIVES AS MGLUR2 ANTAGONISTS I HOFFMANN LA ROCHE (CH) 2005-01-26 EP claimed
US-6548495-B2 Metabotropic glutamate receptor agonist for treatment or prevention of acute and/or chronic neurological disorders HOFFMANN-LA ROCHE INC. 2003-04-15 US claimed
US-20020198197-A1 Dihydro-benzo [b] [1,4] diazepin-2-one derivatives HOFFMANN-LA ROCHE INC. 2002-12-26 US claimed
US-6407094-B1 4-5-DIDEHYDRO-1,5-BENZODIAZEPIN-2-ONE DERIVATIVES; PSYCHOLOGICAL, NERVOUS SYSTEM, AND BRAIN DISORDERS; COGNITION ACTIVATORS; ALZHEIMER*S DISEASE, SCHIZOPHRENIA HOFFMANN-LA ROCHE INC. 2002-06-18 US claimed
EP-4363511-A1 ELECTRODEPOSITABLE COATING COMPOSITIONS PPG Industries Ohio Inc. (US) 2024-05-08 EP disclosed
EP-3580290-B1 LOW-TEMPERATURE CURING COATING COMPOSITIONS PPG IND OHIO INC (US) 2024-05-01 EP disclosed
US-11952514-B2 Low-temperature curing adhesive compositions PPG INDUSTRIES OHIO, INC. (US) 2024-04-09 US disclosed
WO-2023279087-A1 ELECTRODEPOSITABLE COATING COMPOSITIONS PPG INDUSTRIES OHIO, INC. (US) 2023-01-05 WO disclosed
EP-0551675-A1 Oral hygiene compositions containing antiplaque agents UNILEVER N.V. (NL) 1993-07-21 EP disclosed
EP-0550099-A1 Oral hygiene compositions containing amino sugars as antiplaque agents UNILEVER N.V. (NL) 1993-07-07 EP disclosed
US-4563288-A N-Alkyl isostearamide antistatic agents, detergent compositions containing such agents, and processes for washing laundry in the presence of such agents, and with such compositions COLGATE-PALMOLIVE COMPANY (US) 1986-01-07 US disclosed
US-4497715-A N-Alkylisostearamides as antistatic agents COLGATE-PALMOLIVE COMPANY (US) 1985-02-05 US disclosed
US-4283192-A DETERGENTS COLGATE-PALMOLIVE COMPANY (US) 1981-08-11 US disclosed