Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | FDPS | P14324 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.50 |
| ▸ | ABAT | P80404 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433948 | 0.84 | ALDH1A1 (0.64) | ALDH1A1TSHRFDPSLMNAMAPT | |
| SCHEMBL2843898 | 0.83 | ALDH1A1 (0.62) | ALDH1A1TSHRFDPSLMNAMAPT | |
| SCHEMBL2841230 | 0.82 | ALDH1A1 (0.60) | ALDH1A1TSHRFDPSLMNAMAPT | |
| SCHEMBL7661907 | 0.82 | FDPS (0.86) | ALDH1A1TSHRFDPSLMNAMAPT | |
| SCHEMBL5974454 | 0.80 | FDPS (0.77) | ALDH1A1TSHRFDPSLMNAMAPT | |
| SCHEMBL754958 | 0.80 | ALDH1A1 (0.72) | ALDH1A1TSHRFDPSLMNAMAPT | |
| SCHEMBL30416638 | 0.80 | ALDH1A1 (0.72) | ALDH1A1TSHRFDPSLMNAMAPT | |
| 3,4-Dimethoxybenzaldehyde SCHEMBL25202 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TSHRFDPSLMNAMAPT | |
| 3,4-Dimethoxybenzaldehyde SCHEMBL5308959 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TSHRFDPSLMNAMAPT | |
| 3,4-Dimethoxybenzaldehyde SCHEMBL1330962 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TSHRFDPSLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | disclosed |
| US-6479495-B1 | SIMULTANEOUSLY TREATING DEPRESSION AND MEMORY DYSFUNCTION IN MAMMALS SUFFERING FROM MEMORY DYSFUNCTION AND DEPRESSION | AVENTIS PHARMACEUTICALS INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | disclosed |