Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | HTR7 | P34969 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | DRD4 | P21917 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132073 | 0.87 | ALDH1A1 (0.66) | ALDH1A1KDM4EGAATDP1SMN1; SMN2 | |
| SCHEMBL7691290 | 0.86 | ALDH1A1 (0.71) | ALDH1A1KDM4EGAATDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6131815 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KDM4EGAATDP1SMN1; SMN2 | |
| SCHEMBL6132010 | 0.79 | GAA (0.62) | ALDH1A1KDM4EGAATDP1SMN1; SMN2 | |
| SCHEMBL9720648 | 0.79 | HTR7 (0.70) | ALDH1A1KDM4EGAATDP1SMN1; SMN2 | |
| SCHEMBL13559777 | 0.78 | CHKA (0.56) | ALDH1A1KDM4ESMN1; SMN2KMT2ADRD4 | |
| SCHEMBL21221133 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KDM4EGAATDP1SMN1; SMN2 | |
| SCHEMBL8325210 | 0.78 | ALDH1A1 (0.63) | ALDH1A1GAADRD4HTT | |
| SCHEMBL8327595 | 0.76 | ALDH1A1 (0.66) | ALDH1A1GAAMAPK1DRD4LMNA | |
| SCHEMBL6131782 | 0.76 | ALDH1A1 (0.58) | ALDH1A1KDM4EGAATDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | disclosed |
| US-6479495-B1 | SIMULTANEOUSLY TREATING DEPRESSION AND MEMORY DYSFUNCTION IN MAMMALS SUFFERING FROM MEMORY DYSFUNCTION AND DEPRESSION | AVENTIS PHARMACEUTICALS INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | disclosed |