Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131883 | 1.00 | KDM4E (0.53) | KDM4EMAPTLMNAHTTTDP1 | |
| Hydrochloric Acid SCHEMBL6131896 | 0.99 | KDM4E (0.53) | KDM4EMAPTLMNAHTTTDP1 | |
| Hydrochloric Acid SCHEMBL6131823 | 0.93 | KDM4E (0.59) | KDM4EMAPTLMNAHTTTDP1 | |
| SCHEMBL6131975 | 0.86 | BCHE (0.57) | KDM4ETDP1HTR7DRD2DRD4 | |
| SCHEMBL6131859 | 0.85 | ALDH1A1 (0.54) | KDM4EMAPTLMNAHTTTDP1 | |
| SCHEMBL6131848 | 0.85 | ALDH1A1 (0.54) | KDM4EMAPTLMNAHTTTDP1 | |
| Hydrochloric Acid SCHEMBL6131772 | 0.85 | ALDH1A1 (0.54) | KDM4ETDP1HTR7DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL6131817 | 0.85 | BCHE (0.56) | KDM4ETDP1HTR7DRD2DRD4 | |
| SCHEMBL6131963 | 0.83 | KDM4E (0.60) | KDM4EMAPTLMNAHTTTDP1 | |
| SCHEMBL6131927 | 0.80 | KDM4E (0.65) | KDM4EMAPTLMNAHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |