Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 4/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.53 |
| ▸ | RBP4 | P02753 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | EBP | Q15125 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6131923 | 0.99 | ADRA1D (0.52) | ADRA1DADRA1AADRA1BRBP4HTR1A | |
| SCHEMBL6131819 | 0.90 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BRBP4HTR1A | |
| SCHEMBL6131894 | 0.89 | ADRA1D (0.53) | ADRA1DADRA1AADRA1BRBP4HTR1A | |
| SCHEMBL6131790 | 0.87 | ADRA1D (0.57) | ADRA1DADRA1AADRA1BHTR1ASIGMAR1 | |
| SCHEMBL6131925 | 0.87 | ADRA1D (0.57) | ADRA1DADRA1AADRA1BHTR1ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL6131948 | 0.86 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BSIGMAR1KCNH2 | |
| SCHEMBL6131889 | 0.84 | ADRA1D (0.76) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6131810 | 0.83 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BHTR1A | |
| Hydrochloric Acid SCHEMBL6131853 | 0.82 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6131908 | 0.80 | ALDH1A1 (0.58) | ADRA1DADRA1AADRA1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |