Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131859 | 0.86 | ALDH1A1 (0.54) | HTR4ALDH1A1KDM4ECYP2C9CYP2C19 | |
| SCHEMBL6131848 | 0.86 | ALDH1A1 (0.54) | HTR4ALDH1A1KDM4ECYP2C9CYP2C19 | |
| SCHEMBL6131825 | 0.83 | DRD2 (0.58) | HTR4ALDH1A1KDM4ECYP2C9CYP2C19 | |
| SCHEMBL6131809 | 0.81 | DRD2 (0.61) | HTR4ALDH1A1KDM4ECYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL7682482 | 0.80 | DRD2 (0.60) | HTR4ALDH1A1KDM4ECYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL6131976 | 0.79 | DRD2 (0.58) | HTR4ALDH1A1KDM4ECYP2C9CYP2C19 | |
| SCHEMBL6131898 | 0.78 | ALDH1A1 (0.71) | ALDH1A1KDM4EKMT2ALMNASMN1; SMN2 | |
| SCHEMBL7686968 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KDM4ECYP2C9CYP2C19CYP1A2 | |
| SCHEMBL6131919 | 0.76 | ALDH1A1 (0.69) | ALDH1A1KDM4EKMT2ALMNASMN1; SMN2 | |
| Bicarbonate SCHEMBL6131884 | 0.74 | ALDH1A1 (0.51) | ALDH1A1KDM4ECYP2C9CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |