Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD5 | P21918 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3322960 | 0.88 | KDM4E (0.71) | KDM4ETSHRMAPTKMT2ADRD3 | |
| Hydrochloric Acid SCHEMBL3320118 | 0.86 | KDM4E (0.70) | KDM4ETSHRMAPTKMT2ADRD3 | |
| SCHEMBL3049241 | 0.80 | DRD3 (0.71) | KDM4ETSHRMAPTDRD3DRD2 | |
| SCHEMBL3059563 | 0.80 | REV1 (0.66) | KDM4ETSHRMAPTKMT2ADRD3 | |
| SCHEMBL6132003 | 0.79 | KDM4E (0.64) | KDM4ETSHRMAPTKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL6132039 | 0.78 | KDM4E (0.63) | KDM4ETSHRMAPTKMT2AALDH1A1 | |
| SCHEMBL3058767 | 0.76 | KDM4E (0.55) | KDM4ETSHRMAPTKMT2ADRD3 | |
| SCHEMBL10753092 | 0.76 | POLB (0.62) | KDM4ETSHRMAPTKMT2ADRD3 | |
| SCHEMBL3041492 | 0.76 | CA9 (0.69) | KDM4ETSHRMAPTKMT2ADRD3 | |
| SCHEMBL3324219 | 0.74 | KDM4E (0.63) | KDM4ETSHRMAPTKMT2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | disclosed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | disclosed |