Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.58 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.55 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6132039 | 0.99 | KDM4E (0.63) | KDM4ETDP1KMT2AMAPTGAA | |
| SCHEMBL5667128 | 0.82 | DRD2 (0.65) | KDM4EKMT2AMAPTRAB9ADRD2 | |
| SCHEMBL3059243 | 0.82 | REV1 (0.78) | KDM4ETDP1KMT2AMAPTGAA | |
| SCHEMBL7680831 | 0.82 | DRD2 (0.64) | KDM4EKMT2AGAARAB9ADRD2 | |
| Hydrochloric Acid SCHEMBL5667186 | 0.81 | DRD2 (0.64) | KDM4EKMT2AMAPTRAB9ADRD2 | |
| SCHEMBL3059412 | 0.81 | KDM4E (0.86) | KDM4ETDP1KMT2AMAPTGAA | |
| Hydrochloric Acid SCHEMBL6132064 | 0.81 | DRD2 (0.63) | KDM4EKMT2AGAARAB9ADRD2 | |
| SCHEMBL6131905 | 0.81 | DRD2 (0.63) | KDM4EKMT2AGAADRD2ALDH1A1 | |
| Bromide SCHEMBL6132084 | 0.80 | DRD2 (0.61) | KDM4EKMT2AGAADRD2ALDH1A1 | |
| SCHEMBL6132005 | 0.79 | KDM4E (0.59) | KDM4ETDP1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | disclosed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | disclosed |