Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 10/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.81 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 2/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.79 |
| ▸ | HTT | P42858 | 1/20 | 0.79 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.79 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.79 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.74 |
| ▸ | ABCC1 | P33527 | 5/20 | 0.71 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416542 | 0.96 | KDM4E (0.79) | ABCB1KDM4ETDP1PDE4BMAPT | |
| SCHEMBL3059412 | 0.92 | KDM4E (0.86) | ABCB1KDM4ETDP1PDE4BMAPT | |
| SCHEMBL29836069 | 0.88 | KDM4E (0.93) | ABCB1KDM4ETDP1PDE4BMAPT | |
| SCHEMBL3059315 | 0.85 | ABCB1 (0.77) | ABCB1KDM4ETDP1PDE4BMAPT | |
| SCHEMBL3810641 | 0.84 | KMT2A (0.76) | ABCB1KDM4ETDP1MAPTGAA | |
| SCHEMBL3051392 | 0.83 | CA2 (0.73) | ABCB1KDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL3506177 | 0.83 | CA2 (0.73) | ABCB1KDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL30760754 | 0.83 | ABCB1 (1.00) | ABCB1KDM4ETDP1ABCC1ABCG2 | |
| SCHEMBL5131462 | 0.83 | KDM4E (0.71) | ABCB1KDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL3050097 | 0.83 | CA9 (1.00) | ABCB1KDM4ETDP1PDE4BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |