Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28992711 | 0.98 | TDP1 (0.41) | TDP1L3MBTL1LIPGKCNH2TYR | |
| SCHEMBL28547139 | 0.98 | TDP1 (0.41) | TDP1L3MBTL1LIPGKCNH2TYR | |
| SCHEMBL28164575 | 0.98 | TDP1 (0.41) | TDP1L3MBTL1LIPGKCNH2TYR | |
| SCHEMBL28848032 | 0.98 | TDP1 (0.41) | TDP1L3MBTL1LIPGKCNH2TYR | |
| SCHEMBL28164503 | 0.98 | TDP1 (0.41) | TDP1L3MBTL1LIPGKCNH2TYR | |
| SCHEMBL28944228 | 0.84 | CYP2E1 (0.35) | CYP3A4ADRA2AADRA2BADRA2C | |
| Ammonia Solution, Strong SCHEMBL28821972 | 0.82 | CYP2E1 (0.34) | CYP3A4 | |
| SCHEMBL1845714 | 0.81 | TYR (0.40) | TDP1L3MBTL1LIPGKCNH2TYR | |
| SCHEMBL4784302 | 0.79 | TLR8 (0.45) | TDP1L3MBTL1LIPGTLR8KDM4E | |
| SCHEMBL4784300 | 0.79 | TDP1 (0.41) | TDP1L3MBTL1KCNH2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113508112-A | Herbicidal compounds | 先正达农作物保护股份公司 | 2021-10-15 | — | — | CN | disclosed |
| CN-113453553-A | Herbicidal composition | 先正达农作物保护股份公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-113453554-A | Herbicidal composition | 先正达农作物保护股份公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-113423273-A | Herbicidal composition | 先正达农作物保护股份公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-113423272-A | Herbicidal composition | 先正达农作物保护股份公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-113423271-A | Pre-harvest drying method | 先正达农作物保护股份公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-113412054-A | Herbicidal composition | 先正达农作物保护股份公司 | 2021-09-17 | — | — | CN | disclosed |
| CN-111836806-A | Herbicidal compounds | 先正达参股股份有限公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-111032640-A | Herbicidal compounds | 先正达参股股份有限公司 | 2020-04-17 | — | — | CN | disclosed |
| EP-1435957-A4 | INHIBITORS OF GSK-3 AND CRYSTAL STRUCTURES OF GSK-3BETA PROTEIN AND PROTEIN COMPLEXES | VERTEX PHARMA (US) | 2005-04-13 | — | — | EP | disclosed |
| US-20040242886-A1 | Monocyclic diazodioxide based Bcl-2 protein antagonists related applications | RICERCA BIOSCIENCES, LLC. | 2004-12-02 | — | — | US | disclosed |
| WO-2004099158-A1 | MONOCYCLIC DIAZODIOXIDE BASED BCL-2 PROTEIN ANTAGONISTS | RICERCA BIOSCIENCES, LLC. (US) | 2004-11-18 | — | — | WO | disclosed |
| EP-1435957-A2 | INHIBITORS OF GSK-3 AND CRYSTAL STRUCTURES OF GSK-3BETA PROTEIN AND PROTEIN COMPLEXES | Vertex Pharmaceuticals Incorporated (US) | 2004-07-14 | — | — | EP | disclosed |
| EP-1385834-A1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2003027083-A1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2003-04-03 | — | — | WO | disclosed |
| WO-2002088078-A2 | INHIBITORS OF GSK-3 AND CRYSTAL STRUCTURES OF GSK-3β PROTEIN AND PROTEIN COMPLEXES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2002-11-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242886-A1 | Monocyclic diazodioxide based Bcl-2 protein antagonists related applications | BCL2A1, BCL2, BCL2L10 | TDP1 4575/4885L3MBTL1 2107/4885LIPG 4079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.