Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043156 | 1.00 | NAAA (0.44) | NAAAMEN1KMT2ALMNAPOLB | |
| SCHEMBL9042040 | 1.00 | NAAA (0.44) | NAAAMEN1KMT2ALMNAPOLB | |
| SCHEMBL10385001 | 1.00 | NAAA (0.44) | NAAAMEN1KMT2ALMNAPOLB | |
| SCHEMBL4430092 | 0.98 | NAAA (0.41) | NAAAMEN1KMT2ALMNAPOLB | |
| SCHEMBL9032916 | 0.95 | LMNA (0.42) | NAAAMEN1KMT2ALMNAPOLB | |
| SCHEMBL21867399 | 0.94 | LMNA (0.45) | NAAAMEN1KMT2ALMNAPOLB | |
| SCHEMBL9044455 | 0.88 | NAAA (0.44) | NAAAMEN1KMT2ALMNAPOLB | |
| SCHEMBL9043889 | 0.88 | NAAA (0.44) | NAAAMEN1KMT2ALMNAPOLB | |
| SCHEMBL9044854 | 0.88 | NAAA (0.44) | NAAAMEN1KMT2ALMNAPOLB | |
| SCHEMBL26645767 | 0.87 | LMNA (0.50) | NAAAMEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6838574-B1 | Dicarba-closo-dodecarborane derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2005-01-04 | — | — | US | disclosed |
| EP-1145718-A1 | DICARBA-closo-DODECABORANE DERIVATIVES | Institute of Medicinal Molecular Design, Inc. (JP) | 2001-10-17 | — | — | EP | disclosed |
| EP-0698027-A1 | DEOXYTHIOMARINOL DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS MICROBICIDES AND HERBICIDES | SMITHKLINE BEECHAM PLC (GB) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994026750-A1 | DEOXYTHIOMARINOL DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS MICROBICIDES AND HERBICIDES | SMITHKLINE BEECHAM PLC (GB) | 1994-11-24 | — | — | WO | disclosed |