Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 4/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539208 | 0.84 | GFER (0.57) | GFERCASP6MAPTKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6132781 | 0.80 | USP2 (0.57) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8259410 | 0.80 | GFER (0.59) | GFERCASP6MAPTKMT2AMEN1 | |
| SCHEMBL6132455 | 0.78 | ALDH1A1 (0.49) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6132581 | 0.77 | MAPT (0.54) | GFERCASP6MAPTKMT2AMEN1 | |
| SCHEMBL30555283 | 0.76 | USP2 (0.50) | ALDH1A1NAMPTNPC1RAB9AALOX12 | |
| SCHEMBL7313812 | 0.76 | ALDH1A1 (0.50) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL681898 | 0.75 | PDE4B (0.64) | — | |
| SCHEMBL24379449 | 0.75 | USP2 (0.62) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9014134 | 0.74 | CASP6 (0.51) | GFERCASP6KMT2ANAMPTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |