Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10256575 | 0.77 | — | — | |
| SCHEMBL4893881 | 0.75 | SLC18A3 (0.47) | SLC18A3BBOX1 | |
| Iodide SCHEMBL426332 | 0.75 | CHRNA10 (0.33) | — | |
| Iodide SCHEMBL25405847 | 0.74 | KDM4E (0.50) | SLC18A3ALDH1A1HPGDKMT2ABBOX1 | |
| Iodide SCHEMBL14778907 | 0.72 | KDM4E (0.54) | SLC18A3ALDH1A1HPGDKMT2ABBOX1 | |
| SCHEMBL739073 | 0.72 | TRIM24 (0.32) | ALDH1A1 | |
| SCHEMBL8346719 | 0.71 | BBOX1 (0.34) | BBOX1 | |
| SCHEMBL3817323 | 0.71 | — | — | |
| SCHEMBL25557911 | 0.71 | — | — | |
| Bromide SCHEMBL4087944 | 0.70 | TRIM24 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |